Background Understanding the neurobiological underpinnings of childhood maltreatment is
vital given consistent links with poor mental health. Dimensional models of adversity purport …

Background Childhood maltreatment is associated with lifelong psychiatric sequelae.
However, our understanding of neurobiological mechanisms responsible for this association …

The experience of childhood maltreatment is related to an increased risk of developing a
variety of psychiatric disorders, as well as a change in the structure of the brain. However …

Childhood adversity represents a major risk factor for drug addiction and other mental
disorders. However, the specific mechanisms by which childhood adversity impacts human …

Childhood maltreatment (CM) confers a great risk of maladaptive development outcomes
later in life, however, the neurobiological mechanism underlying this vulnerability is still …

Background Childhood maltreatment is a major risk factor for psychopathology. However,
some maltreated individuals appear remarkably resilient to the psychiatric effects while …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

Childhood maltreatment is associated with alterations in neural architecture that potentially
put these children at increased risk for psychopathology. Alterations in white matter (WM) …

Importance More than 10% of children experience sexual, physical, or emotional abuse, and
abuse experienced during sensitive neurodevelopmental periods is associated with a …

Different dimensions of adversity may affect mental health through distinct neurobiological
mechanisms, though current supporting evidence consists largely of cross-sectional …