Altered brain activity and functional connectivity after MDMA-assisted therapy for post-traumatic stress disorder
Introduction 3, 4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-
traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials. MDMA …
traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials. MDMA …
[HTML][HTML] MDMA-assisted psychotherapy for PTSD: Are memory reconsolidation and fear extinction underlying mechanisms?
AA Feduccia, MC Mithoefer - Progress in neuro-psychopharmacology and …, 2018 - Elsevier
MDMA-assisted psychotherapy for treatment of PTSD has recently progressed to Phase 3
clinical trials and received Breakthrough Therapy designation by the FDA. MDMA used as …
clinical trials and received Breakthrough Therapy designation by the FDA. MDMA used as …
Scaling up: multisite open-label clinical trials of MDMA-assisted therapy for severe posttraumatic stress disorder
JB Wang, J Lin, L Bedrosian, A Coker… - Journal of …, 2021 - journals.sagepub.com
Background: Posttraumatic stress disorder (PTSD) is a debilitating mental health condition
associated with serious adverse health outcomes and functional impairment. Previous …
associated with serious adverse health outcomes and functional impairment. Previous …
Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3, 4-methylenedioxymethamphetamine (MDMA)
MB Young, SD Norrholm, LM Khoury, T Jovanovic… - …, 2017 - Springer
Abstract Rationale 3, 4-Methylenedioxymethamphetamine (MDMA) persistently improves
symptoms of post-traumatic stress disorder (PTSD) when combined with psychotherapy …
symptoms of post-traumatic stress disorder (PTSD) when combined with psychotherapy …
Exposure‐based therapy changes amygdala and hippocampus resting‐state functional connectivity in patients with posttraumatic stress disorder
Background Recent research suggests that posttraumatic stress disorder (PTSD) is
associated with altered amygdala and hippocampal resting‐state functional connectivity …
associated with altered amygdala and hippocampal resting‐state functional connectivity …
[HTML][HTML] MDMA-assisted psychotherapy for PTSD: Growing evidence for memory effects mediating treatment efficacy
The application of MDMA in conjunction with psychotherapy has in recent years seen a
resurgence of clinical, scientific, and public interest in the treatment of posttraumatic stress …
resurgence of clinical, scientific, and public interest in the treatment of posttraumatic stress …
A proposed mechanism for the MDMA-mediated extinction of traumatic memories in PTSD patients treated with MDMA-assisted therapy
RJ Sottile, T Vida - Frontiers in psychiatry, 2022 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a devastating psychiatric disorder afflicting millions
of people around the world. Characterized by severe anxiety, intrusive thoughts, pervasive …
of people around the world. Characterized by severe anxiety, intrusive thoughts, pervasive …
Effects of 3, 4-methylenedioxymethamphetamine on conditioned fear extinction and retention in a crossover study in healthy subjects
P Vizeli, I Straumann, U Duthaler… - Frontiers in …, 2022 - frontiersin.org
Background: 3, 4-Methylenedioxymethamphetamine (MDMA) has shown initial promise as
an adjunct in psychotherapy to treat posttraumatic stress disorder (PTSD). Its efficacy and …
an adjunct in psychotherapy to treat posttraumatic stress disorder (PTSD). Its efficacy and …
MDMA-assisted therapy for posttraumatic stress disorder: A pooled analysis of ethnoracial differences in efficacy and safety from two Phase 2 open-label lead-in trials …
Background: Limited ethnoracial diversity in previous±3, 4-
methylenedioxymethamphetamine-assisted therapy (MDMA-AT) trials for posttraumatic …
methylenedioxymethamphetamine-assisted therapy (MDMA-AT) trials for posttraumatic …
Efficacy of 3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for posttraumatic stress disorder: a systematic review and meta-analysis
Background Posttraumatic stress disorder (PTSD) is a common psychiatric condition that
can develop following a traumatic experience. PTSD is associated with significant disability …
can develop following a traumatic experience. PTSD is associated with significant disability …