The air-liquid interface of the mammalian lung is lined with pulmonary surfactants, a mixture
of specific proteins and lipids that serve a dual purpose-enabling air-breathing and …

Phylogenetic analyses of the families of mammalian lung surfactant proteins (SP-A, SP-B,
SP-C, and SP-D) supported the hypothesis that these proteins have diverged between birds …

Surface tension is reduced at the air–liquid interface in the lung by a mixture of lipids and
proteins termed pulmonary surfactant. This study is the first to provide evidence for the …

Pulmonary surfactant protein A (SP-A) plays a key role in innate lung host defense, in
surfactant-related functions, and in parturition. In the course of evolution, the genetic …

Surfactant protein A (SP-A) and D (SP-D) are hydrophilic collagenous C-type lectins, which
were originally discovered in the lungs associated with surfactant phospholipids. It was later …

Surfactant protein A (SP-A) constitutes an important part of the innate immune defense in the
lung. In humans there are two functional genes (SP-A1 and SP-A2). The functional …

For years, the so-called surfactant proteins (SPs) that were discovered in the phospholipid-
rich material designated pulmonary surfactant, were considered to be lung-specific. The fact …

Surfactant protein A (SP-A) constitutes an important part of the innate immune defense in the
lung. In humans there are two functional genes (SP-A1 and SP-A2). The functional …

The gene encoding surfactant protein A (SP-A) is expressed in type II pneumonocytes and is
developmentally and hormonally regulated in fetal lung tissue. SP-A is encoded by a single …

Abstract Surfactant Protein A (SP-A) is a collagenous C-type lectin (collectin) that plays an
important role in the early stage of the host immune response. In chicken, SP-A (cSP-A) is …