Abstract Alzheimer's disease (AD), the most common cause of dementia worldwide, has
gradually become a global health concern for society and individuals with the process of …

Neural stem cells (NSC) are cells that have the capacity to generate multiple types of
differentiated brain cells. In conditions in which there is a loss of key functional cell groups …

Recent studies have demonstrated that neuroplasticity, such as synaptic plasticity and
neurogenesis, exists throughout the normal lifespan but declines with age and is …

Two of the most common neurodegenerative disorders–Alzheimer's and Parkinson's
diseases–are characterized by synaptic dysfunction and degeneration that culminate in …

Neurogenesis is maintained in both neonatal and adult brain, although it is dramatically
reduced in aged neurogenic brain region such as the subgranular layer and subventricular …

Identifying novel, effective therapeutics for Alzheimer's disease (AD) is one of the major
unmet medical needs for the coming decade. Because the current paradigm for developing …

Abstract Alzheimer's disease (AD), at present, is considered an incurable disease and a
major dilemma with no drug to stop or slow down its progression. Drugs that are currently …

Alzheimer's disease (AD) is a recognized incurable neurodegenerative disorder. Clinically
prescribed medicines for AD are expected to bring about only slight symptomatic …

In this review, we consider the evidence that a reduction in neurogenesis underlies aging-
related cognitive deficits and impairments in disorders such as Alzheimer's disease (AD) …

Alzheimer's disease cannot be cured as of yet. Our current understanding on the causes of
Alzheimer's disease is limited. To develop treatments, experimental models that represent a …