Rationale: Gustation is important to several biological functions in mammals. However,
chemotherapy drugs often harm taste perception in cancer patients, while the underlying …

As one of the adverse effects of oxaliplatin, a key agent in colon cancer chemotherapy, a
taste disorder is a severe issue in a clinical situation because it decreases the quality of life …

Taste disorders are common adverse effects of cancer chemotherapy that can reduce quality
of life and impair nutritional status. However, the molecular mechanisms underlying …

Since the early 20th century, progress in cancer therapies has significantly improved
disease prognosis. Nonetheless, cancer treatments are often associated with side effects …

Background Taste disorders are frequently observed in cancer patients undergoing
chemotherapy and are serious adverse events which impair the quality of life (QoL) of the …

The sense of taste is responsible for the detection and ingestion of food to cover energetic
requirements in health and disease. The change in taste perception might lead to …

Two of the highest prevalent symptoms reported by cancer patients are taste dysfunction
(17.6–93%) and dry mouth/xerostomia (40.4–93%). While it has been hypothesized that …

Simple Summary Bitter taste receptors (TAS2Rs) are functionally expressed in various extra-
oral cells eliciting non-gustatory functions. In the context of cancer, their functionality is less …

Many common chemotherapeutics produce disruptions in the sense of taste which can lead
to loss of appetite, nutritional imbalance, and reduced quality of life, especially if taste loss …

Taste and smell disorders (TSDs) are common side effects in patients undergoing cancer
treatments. Knowing which treatments specifically cause them is crucial to improve patients' …