Protein-Engineered Fibers For Drug Encapsulation Traceable via 19F Magnetic Resonance

D Britton, J Legocki, O Aristizabal… - ACS Applied Nano …, 2023 - ACS Publications
Theranostic materials research is experiencing rapid growth driven by the interest in
integrating both therapeutic and diagnostic modalities. These materials offer the unique …

Protein-Engineered Nanoscale Micelles for Dynamic 19F Magnetic Resonance and Therapeutic Drug Delivery

LK Hill, JA Frezzo, P Katyal, DM Hoang… - ACS …, 2019 - ACS Publications
Engineered proteins provide an interesting template for designing fluorine-19 (19F)
magnetic resonance imaging (MRI) contrast agents, yet progress has been hindered by the …

Glyconanofluorides as immunotracers with a tunable core composition for sensitive hotspot magnetic resonance imaging of inflammatory activity

D Cohen, R Mashiach, L Houben, A Galisova… - ACS …, 2021 - ACS Publications
Nature-inspired nanosized formulations based on an imageable, small-sized inorganic core
scaffold, on which biomolecules are assembled to form nanobiomimetics, hold great …

Multivalent Fluorinated Nanorings for On-Cell 19F NMR

J Li, Y Wang, MD Distefano, CR Wagner… - …, 2024 - ACS Publications
The design of imaging agents with a high fluorine content is necessary for overcoming the
challenges of low sensitivity in 19F magnetic resonance imaging (MRI)-based molecular …

Fluorine Meets Amine: Reducing Microenvironment-Induced Amino-Activatable Nanoprobes for 19F-Magnetic Resonance Imaging of Biothiols

P Huang, W Guo, G Yang, H Song… - … applied materials & …, 2018 - ACS Publications
19F-magnetic resonance imaging (MRI) is of great significance for noninvasive imaging and
detection of various diseases. However, the main obstacle in the application of 19F-MRI …

Self‐Assembled Fluorinated Nanoparticles as Sensitive and Biocompatible Theranostic Platforms for 19F MRI

D Havlicek, VM Panakkal, L Voska… - Macromolecular …, 2024 - Wiley Online Library
Theranostics is a novel paradigm integrating therapy and diagnostics, thereby providing
new prospects for overcoming the limitations of traditional treatments. In this context …

Engineered protein–iron oxide hybrid biomaterial for MRI-traceable drug encapsulation

LK Hill, D Britton, T Jihad, K Punia, X Xie… - … systems design & …, 2022 - pubs.rsc.org
Labeled protein-based biomaterials have become popular for various biomedical
applications such as tissue-engineered, therapeutic, and diagnostic scaffolds. Labeling of …

Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imaging

M Srinivas, LJ Cruz, F Bonetto, A Heerschap… - Biomaterials, 2010 - Elsevier
Monitoring cell trafficking in vivo noninvasively is critical to improving cellular therapeutics,
drug delivery, and understanding disease progression. In vivo imaging, of which magnetic …

Ultrahigh 19F Loaded Cu1.75S Nanoprobes for Simultaneous 19F Magnetic Resonance Imaging and Photothermal Therapy

H Chen, M Song, J Tang, G Hu, S Xu, Z Guo, N Li… - ACS …, 2016 - ACS Publications
19F magnetic resonance imaging (MRI) is a powerful noninvasive, sensitive, and accurate
molecular imaging technique for early diagnosis of diseases. The major challenge of 19F …

Fluorinated peptide biomaterials

JN Sloand, MA Miller, SH Medina - Peptide Science, 2021 - Wiley Online Library
Fluorinated compounds, while rarely used by nature, are emerging as fundamental
ingredients in biomedical research, with applications in drug discovery, metabolomics …