Broadening horizons: The role of ferroptosis in myocardial ischemia–reperfusion injury

K Zhao, X Chen, Y Bian, Z Zhou, X Wei… - … Archives of Pharmacology, 2023 - Springer
Ferroptosis is a novel type of regulated cell death (RCD) discovered in recent years, where
abnormal intracellular iron accumulation leads to the onset of lipid peroxidation, which …

Ferroptosis: opportunities and challenges in myocardial ischemia‐reperfusion injury

W Zhao, Y Zhou, T Xu, Q Wu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
Ferroptosis is a newly discovered form of regulated cell death dependent on iron and
reactive oxygen species (ROS). It directly or indirectly affects the activity of glutathione …

Targeting ferroptosis: a novel insight against myocardial infarction and ischemia–reperfusion injuries

X Han, J Zhang, J Liu, H Wang, F Du, X Zeng, C Guo - Apoptosis, 2023 - Springer
Ferroptosis, a newly discovered form of regulated cell death dependent on iron and reactive
oxygen species, is mainly characterized by mitochondrial shrinkage, increased density of …

[HTML][HTML] Ferroptosis as a novel therapeutic target for cardiovascular disease

X Wu, Y Li, S Zhang, X Zhou - Theranostics, 2021 - ncbi.nlm.nih.gov
Cell death is an important component of the pathophysiology of cardiovascular disease. An
understanding of how cardiomyocytes die, and why regeneration of cells in the heart is …

[HTML][HTML] A novel insight into the fate of cardiomyocytes in ischemia-reperfusion injury: from iron metabolism to ferroptosis

J Li, S Liu, R Yao, Y Tian, Y Yao - Frontiers in Cell and …, 2021 - frontiersin.org
Ischemia-reperfusion injury (IRI), critically involved in the pathology of reperfusion therapy
for myocardial infarction, is closely related to oxidative stress the inflammatory response …

[HTML][HTML] Ferroptosis in cardiovascular diseases: role and mechanism

Q Zhang, Y Luo, L Peng, X Rong, Y Liu, J Li, J Luo - Cell & Bioscience, 2023 - Springer
In multicellular organisms, regulatory cell death is a crucial aspect of growth and
development. Ferroptosis, which was postulated roughly ten years ago, is a mode of cell …

[HTML][HTML] New insights into the role of ferroptosis in cardiovascular diseases

AM Fratta Pasini, C Stranieri, F Busti, EG Di Leo… - Cells, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the principal cause of disease burden and death
worldwide. Ferroptosis is a new form of regulated cell death mainly characterized by altered …

[HTML][HTML] Ferroptosis—a new dawn in the treatment of organ ischemia–reperfusion injury

L Zhou, S Han, J Guo, T Qiu, J Zhou, L Shen - Cells, 2022 - mdpi.com
Ischemia–reperfusion (I/R) is a common pathological phenomenon that occurs in numerous
organs and diseases. It generally results from secondary damage caused by the recovery of …

[HTML][HTML] Ferroptosis is a potential novel diagnostic and therapeutic target for patients with cardiomyopathy

Z Zhai, P Zou, F Liu, Z Xia, J Li - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Cardiomyocyte death is a fundamental progress in cardiomyopathy. However, the
mechanism of triggering the death of myocardial cells remains unclear. Ferroptosis, which is …

[HTML][HTML] Ferroptosis: a new strategy for cardiovascular disease

Y Wang, J Wu - Frontiers in Cardiovascular Medicine, 2023 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is currently one of the prevalent causes of human death. Iron
is one of the essential trace elements in the human body and a vital component of living …