Phenotypic and Functional Diversity of Neutrophils in Gut Inflammation and Cancer
R Sumagin - The American Journal of Pathology, 2023 - Elsevier
Neutrophils (PMNs) execute important effector functions protecting the host against invading
pathogens, however their activity in tissue can exacerbate inflammation and inflammation …
pathogens, however their activity in tissue can exacerbate inflammation and inflammation …
Tumor-associated neutrophils: orchestrating cancer pathobiology and therapeutic resistance
Introduction: Neutrophils or polymorphonuclear cells (PMNs) account for a considerable
portion of the tumor immune stroma. Emerging single-cell transcriptomic analyses have …
portion of the tumor immune stroma. Emerging single-cell transcriptomic analyses have …
[HTML][HTML] Pathobiology of the neutrophil-intestinal epithelial cell interaction: role in carcinogenesis
PM Hofman - World journal of gastroenterology: WJG, 2010 - ncbi.nlm.nih.gov
The role of chronic inflammation, acting as an independent factor, on the onset of
gastrointestinal carcinogenesis is now well accepted. However, even if there is an increase …
gastrointestinal carcinogenesis is now well accepted. However, even if there is an increase …
Neutrophil plasticity in the tumor microenvironment
MA Giese, LE Hind… - Blood, The Journal of the …, 2019 - ashpublications.org
Neutrophils act as the body's first line of defense against infection and respond to diverse
inflammatory cues, including cancer. Neutrophils display plasticity, with the ability to adapt …
inflammatory cues, including cancer. Neutrophils display plasticity, with the ability to adapt …
Contributions of neutrophils to resolution of mucosal inflammation
SP Colgan, SF Ehrentraut, LE Glover, DJ Kominsky… - Immunologic …, 2013 - Springer
Neutrophil (PMN) recruitment from the blood stream into surrounding tissues involves a
regulated series of events central to acute responses in host defense. Accumulation of PMN …
regulated series of events central to acute responses in host defense. Accumulation of PMN …
Neutrophils: orchestrators of the malignant phenotype
Neutrophils are the first leukocytes recruited to sites of inflammation, where they execute anti-
microbial functions to eliminate infectious agents. These functions include phagocytosis …
microbial functions to eliminate infectious agents. These functions include phagocytosis …
Tissue-specific reprogramming leads to angiogenic neutrophil specialization and tumor vascularization in colorectal cancer
TM Bui, LK Yalom, E Ning… - The Journal of …, 2024 - Am Soc Clin Investig
Neutrophil (PMN) tissue accumulation is an established feature of ulcerative colitis (UC)
lesions and colorectal cancer (CRC). To assess the PMN phenotypic and functional …
lesions and colorectal cancer (CRC). To assess the PMN phenotypic and functional …
Roles of neutrophils in cancer growth and progression
MR Galdiero, G Varricchi, S Loffredo… - Journal of leukocyte …, 2018 - academic.oup.com
Chronic inflammation is a well-known tumor-enabling capacity, which allows nascent tumors
to acquire all the hallmark capabilities, including the escape from immunosurveillance …
to acquire all the hallmark capabilities, including the escape from immunosurveillance …
Neutrophil heterogeneity in cancer: from biology to therapies
P Lecot, M Sarabi, M Pereira Abrantes… - Frontiers in …, 2019 - frontiersin.org
Neutrophils have been extensively described in the pathophysiology of autoimmune and
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …
Tumor-associated neutrophils
Neutrophils constitute an important component of the innate immune response and are
classically involved in the defense against microorganisms due to their ability to produce …
classically involved in the defense against microorganisms due to their ability to produce …