An individuality of response to cannabinoids: challenges in safety and efficacy of cannabis products

S Kitdumrongthum, D Trachootham - Molecules, 2023 - mdpi.com
Since legalization, cannabis/marijuana has been gaining considerable attention as a
functional ingredient in food.∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other …

Cannabis and cannabinoids: kinetics and interactions

BC Foster, H Abramovici, CS Harris - The American journal of medicine, 2019 - Elsevier
Cannabis sativa and related products are widely used, but their potential to cause significant
clinical interactions remains unclear, particularly for cannabinoid-enriched or otherwise …

Advancing the science on cannabis concentrates and behavioural health

LC Bidwell, R Martin‐Willett… - Drug and Alcohol …, 2021 - Wiley Online Library
Abstract Issues The Cannabis sativa L. plant contains hundreds of phytocannabinoids, but
putatively of highest importance to public health risk is the psychoactive cannabinoid delta‐9 …

Cannabis edibles: dosing, encapsulation, and stability considerations

IP Marangoni, AG Marangoni - Current Opinion in Food Science, 2019 - Elsevier
The recent legalization of marijuana in Canada and several states in the United States of
America has caused a veritable race to develop new products containing cannabinoids …

Factors that impact the pharmacokinetic and pharmacodynamic effects of cannabis: a review of human laboratory studies

CA Zamarripa, R Vandrey, TR Spindle - Current Addiction Reports, 2022 - Springer
Abstract Purpose of Review With cannabis legalization expanding throughout the world, an
unprecedented number of people now have access to legal cannabis. This expanded …

Cannabis: an overview of its adverse acute and chronic effects and its implications

TC Ford, AC Hayley, LA Downey… - Current drug abuse …, 2017 - ingentaconnect.com
In many communities, cannabis is perceived as a low-risk drug, leading to political lobbying
to decriminalise its use. Acute and chronic cannabis use has been shown to be harmful to …

Cannabis, a complex plant: different compounds and different effects on individuals

Z Atakan - Therapeutic advances in psychopharmacology, 2012 - journals.sagepub.com
Cannabis is a complex plant, with major compounds such as delta-9-tetrahydrocannabinol
and cannabidiol, which have opposing effects. The discovery of its compounds has led to …

Synthetic cannabinoids: the hidden side of Spice drugs

N Pintori, B Loi, M Mereu - Behavioural pharmacology, 2017 - journals.lww.com
Spice drugs are herbal mixtures sprayed with synthetic cannabinoids designed to mimic the
psychoactive ingredient in marijuana [Δ 9-tetrahydrocannabinol (Δ 9-THC)] and synthesized …

The health effects of cannabis and cannabinoids: the current state of evidence and recommendations for research

National Academies of Sciences, Medicine Division… - 2017 - books.google.com
Significant changes have taken place in the policy landscape surrounding cannabis
legalization, production, and use. During the past 20 years, 25 states and the District of …

Cannabinoid profiles in medical cannabis users: effects of age, gender, symptoms, and duration of use

M Kalaba, MA Ware - Cannabis and Cannabinoid Research, 2022 - liebertpub.com
Introduction: Clinical trials remain the gold standard for evaluating efficacy, but there is
increasing interest in using real-world evidence (RWE) to inform health care decision …