Citalopram is the most potent selective serotonin reuptake inhibitor, commonly prescribed as
an antidepressant, which can cause sexual dysfunction. Melatonin is a natural, highly …

There is growing concern that some cytotoxic regimens for cancer adversely affect
spermatogenesis and male fertility. Increasing evidence demonstrated that melatonin has …

There is a growing concern that antidepressant drugs impair sexual function and adversely
impact spermatogenesis and male fertility. Vitamin C is a natural antioxidant that plays a vital …

As a chemotherapeutic drug, cyclophosphamide (CP) has a negative impact on male fertility
due to its reproductive toxicity. Melatonin (Mel) promotes the male reproductive system and …

Decline in semen quality has become a global public health concern. Psychological stress is
common in the current modern society and is associated with semen decline. Increasing …

Diquat is a fast, potent, and widely used bipyridine herbicide in agriculture and it induces
oxidative stress in several animal models. However, its genotoxic effects on the male …

Busulfan is a widely used chemotherapeutic drug for chronic myelogenous leukemia and
bone marrow transplantation. As a cell cycle nonspecific alkylation agent, busulfan has a …

Cisplatin (CDDP) is a chemotherapeutic drug that is used to treat many different types of
tumors. However, it also has significant adverse effects on male reproduction, which are …

Oxidative stress generates a large amount of reactive oxygen species (ROS) and affects
sperm quality via damaging sperm DNA and compromising the intracellular homeostasis in …

Objective To determine the protective effects of exogenous melatonin following exposure to
Bleomycin, Etoposide, and Cisplatin (BEP) chemotherapy on sperm parameters and DNA …