The heterocyclic scaffolds are common motifs found in various synthetic molecules with
interesting biological activities. This chapter presents a comprehensive overview on the …

Conspectus The widespread presence of hydrocarbons makes C–H functionalization an
attractive alternative to traditional cross-coupling methods. As indole is an important …

Indole is an important heteroarene feature in many bioactive compounds, natural products,
and functional materials. Hence, diversification of indoles by transition metal‐catalyzed …

Indoles are valuable precursors in medicinal, bioorganic, and material chemistry and
particularly serve as a platform for diversity. However, the scope of the C6-functionalization …

The site-selective C–H bond functionalization of heteroarenes can eventually provide
chemists with great techniques for editing and building complex molecular scaffolds. During …

Indolines could be successfully applied in the diversity of C H bond functionalization of
benzenoid moiety without the competition between sp3 H and sp2 H activations thereby …

The indole scaffold will continue to play a vital part in the future of drug discovery and
agrochemical development. Because of this, the necessity for elegant techniques to enable …

C7-Decorated indoles are important structural motifs present in a plethora of bioactive and
pharmaceutical compounds. Early stage developments for C7 modifications were realized …

C4-Functionalized indole scaffolds are ubiquitous in natural products, bioactive compounds,
and pharmaceuticals. Much effort has thus been made to develop effective synthetic …

Indole is an important structural motif of various drugs, therapeutic leads besides its
prevalence in numerous natural products, agrochemicals, perfumery, and dyes. More than …