The emergence of vaccine-evading SARS-CoV-2 variants urges the need for vaccines that
elicit broadly neutralizing antibodies (bnAbs). Here, we assess covalently circularized …

Vaccination against SARS-CoV-2 provides an effective tool to combat the COVID-19
pandemic. Here, we combined antigen optimization and nanoparticle display to develop …

Rapid emergence of the SARS-CoV-2 variants has dampened the protective efficacy of
existing authorized vaccines. Nanoparticle platforms offer a means to improve vaccine …

We present a comprehensive vaccine strategy for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) by combining antigen optimization and nanoparticle display …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
poses continuous challenges in combating the virus. Here, we describe vaccination …

A safe, effective, and scalable vaccine is needed to halt the ongoing SARS-CoV-2
pandemic. We describe the structure-based design of self-assembling protein nanoparticle …

The current vaccine development strategies for the COVID-19 pandemic utilize whole
inactive or attenuated viruses, virus-like particles, recombinant proteins, and antigen-coding …

The COVID-19 pandemic underscores the need for rapid, safe, and effective vaccines. In
contrast to some traditional vaccines, nanoparticle-based subunit vaccines are particularly …

Antigens displayed on self-assembling nanoparticles can stimulate strong immune
responses and have been playing an increasingly prominent role in structure-based …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has caused the global
pandemic. The virus is rapidly evolving, characterized by the emergence of several major …