Bile acid homeostasis plays a key role in human health. Environmental exposure to
antibiotics may influence bile acid homeostasis, but relevant data remain limited in human …

Bile acid homeostasis is critical to human health. Low-level exposure to antibiotics has been
suggested to potentially disrupt bile acid homeostasis by affecting gut microbiota, but …

The bile acid-liver-gut microbiota axis plays an important role in the host's health. The gut
microbiota has an impact on the bile acid pool, but also the bile acids themselves can …

Bile acid homeostasis plays an important role in many biological activities through the bile–
liver–gut axis. In this study, two in vitro models were applied to further elucidate the mode of …

Various environmental factors can alter the gut microbiome's composition and functionality,
and modulate host health. In this study, the effects of oral and parenteral administration of …

Bile acids are synthesized from cholesterol and play an important role in regulating intestinal
microflora. The different degrees of hydrophobicity and acidity of individual bile acids may …

Bile acids (BAs) are a complex class of metabolites that have been described as specific
biomarkers of gut microbiota activity. The development of analytical methods allowing the …

Antibiotics ingested in the human gut may create selective pressure to change the
composition of the gut microbiota, which could adversely effect the immune system of the …

We elucidate the detailed effects of gut microbial depletion on the bile acid sub-metabolome
of multiple body compartments (liver, kidney, heart, and blood plasma) in rats. We use a …

Many current experiments investigating the effects of diet, dietary supplements, and pre-and
probiotics on the intestinal environments do not take into consideration the potential for …