Myeloid cells, comprised of macrophages, dendritic cells, monocytes, and granulocytes,
represent a major component of the tumor microenvironment (TME) and are critically …

Tumors of various histological origins show abundant infiltration of myeloid cells from early
stages of disease progression. These cells have a profound impact on antitumor immunity …

The versatility and plasticity of myeloid cell polarization/differentiation has turned out to be
crucial in health and disease, and has become the subject of intense investigation during …

The generation of an inflammatory environment is favorable and often decisive for the
growth of both primary tumors and metastases. Tumor cells either express membrane …

Myeloid cells are the most abundant cells in the tumor microenvironment (TME). The tumor
recruits and modulates endogenous myeloid cells to tumor-associated macrophages (TAM) …

For decades, cancer was considered a disease driven by genetic mutations in tumor cells,
therefore afflicting a single cell type. This simplified view was slowly replaced by the …

Our current understanding of human tumor-resident myeloid cells is, for the most part, based
on a large body of work in murine models or studies enumerating myeloid cells in patient …

Tumor‐associated macrophages (TAMs) are a key component of the tumor
microenvironment and orchestrate various aspects of cancer. Diversity and plasticity are …

A bottleneck for immunotherapy of cancer is the immunosuppressive microenvironment in
which the tumor cells proliferate. Cancers harness the immune regulatory mechanism that …

Myeloid cells are a heterogeneous population of bone marrow‐derived cells that play a
critical role during growth and metastasis of malignant tumors. Tumors exhibit significant …