Integration of human and viral miRNAs in Epstein-Barr virus-associated tumors and implications for drug repurposing
Epstein-Barr virus (EBV) is associated with several tumors, and has substantial relevance for
public health. Therapeutics innovation for EBV-related disorders is much needed. In this …
public health. Therapeutics innovation for EBV-related disorders is much needed. In this …
Comprehensive profiling of functional Epstein-Barr virus miRNA expression in human cell lines
MJG Hooykaas, E Kruse, EJHJ Wiertz, RJ Lebbink - BMC genomics, 2016 - Springer
Abstract Background Epstein-Barr virus (EBV) establishes lifelong infections in its human
host. The virus is associated with a broad range of malignancies of lymphoid and epithelial …
host. The virus is associated with a broad range of malignancies of lymphoid and epithelial …
EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape
The Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of
primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the …
primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the …
Comprehensive profiling of Epstein-Barr virus-encoded miRNA species associated with specific latency types in tumor cells
HJ Yang, TJ Huang, CF Yang, LX Peng, RY Liu… - Virology journal, 2013 - Springer
Abstract Background Epstein-Barr virus (EBV) is an etiological cause of many human
lymphocytic and epithelial malignancies. EBV expresses different genes that are associated …
lymphocytic and epithelial malignancies. EBV expresses different genes that are associated …
Comparing proteomics and RISC immunoprecipitations to identify targets of Epstein-Barr viral miRNAs
M Kuzembayeva, YF Chiu, B Sugden - 2012 - journals.plos.org
Epstein-Barr virus is a gamma-herpes virus that is causally associated with several
lymphomas and carcinomas. This virus encodes at least 25 pre-miRNAs, which are …
lymphomas and carcinomas. This virus encodes at least 25 pre-miRNAs, which are …
EBV miRNA expression profiles in different infection stages: A prospective cohort study
A Hartung, O Makarewicz, R Egerer, M Karrasch… - PLoS …, 2019 - journals.plos.org
The Epstein-Barr virus (EBV) produces different microRNAs (miRNA) with distinct regulatory
functions within the infectious cycle. These viral miRNAs regulate the expression of viral and …
functions within the infectious cycle. These viral miRNAs regulate the expression of viral and …
The viral and cellular microRNA targetome in lymphoblastoid cell lines
RL Skalsky, DL Corcoran, E Gottwein, CL Frank… - PLoS …, 2012 - journals.plos.org
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral …
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral …
Characterization of Epstein-Barr virus miRNAome in nasopharyngeal carcinoma by deep sequencing
SJ Chen, GH Chen, YH Chen, CY Liu, KP Chang… - PloS one, 2010 - journals.plos.org
Virus-encoded microRNAs (miRNAs) have been shown to regulate a variety of biological
processes involved in viral infection and viral-associated pathogenesis. Epstein-Barr virus …
processes involved in viral infection and viral-associated pathogenesis. Epstein-Barr virus …
The roles of EBV-encoded microRNAs in EBV-associated tumors
M Dong, J Chen, J Huang, L Gong, C Shao - Critical reviews in oncology …, 2019 - Elsevier
Epstein-Barr virus (EBV) is believed to be a pathogen causing a number of human cancers,
but the pathogenic mechanisms remain unclear. An increasing number of studies have …
but the pathogenic mechanisms remain unclear. An increasing number of studies have …
Novel approach to identify putative Epstein–Barr–virus microRNAs regulating host cell genes with relevance in tumor biology and immunology
S Jasinski-Bergner, J Blümke, M Bauer… - …, 2022 - Taylor & Francis
ABSTRACT The human Epstein–Barr virus is associated with several human solid and
hematopoietic malignancies. However, the underlying molecular mechanisms including …
hematopoietic malignancies. However, the underlying molecular mechanisms including …
相关搜索
- epstein barr comprehensive profiling
- epstein barr drug repurposing
- epstein barr viral mirnas
- epstein barr tumor cells
- epstein barr nasopharyngeal carcinoma
- potent effectors ebv mirnas
- tumor cells mirna species
- virus micrornas tumor biology
- immune escape ebv mirnas
- epstein barr deep sequencing
- epstein barr mirna species
- epstein barr mirna expression
- epstein barr cell lines