Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice
A Parrish, M Boudaud, ET Grant, S Willieme… - Nature …, 2023 - nature.com
Alterations in the gut microbiome, including diet-driven changes, are linked to the rising
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …
Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis
Intestinal adaptive immune responses influence host health, yet only a few intestinal
bacteria species that induce cognate adaptive immune responses during homeostasis have …
bacteria species that induce cognate adaptive immune responses during homeostasis have …
Commensal bacteria protect against food allergen sensitization
AT Stefka, T Feehley, P Tripathi, J Qiu… - Proceedings of the …, 2014 - National Acad Sciences
Environmentally induced alterations in the commensal microbiota have been implicated in
the increasing prevalence of food allergy. We show here that sensitization to a food allergen …
the increasing prevalence of food allergy. We show here that sensitization to a food allergen …
Interspecies commensal interactions have nonlinear impacts on host immunity
The impacts of individual commensal microbes on immunity and disease can differ
dramatically depending on the surrounding microbial context; however, the specific bacterial …
dramatically depending on the surrounding microbial context; however, the specific bacterial …
Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila
Epithelial cells of the mammalian intestine are covered with a mucus layer that prevents
direct contact with intestinal microbes but also constitutes a substrate for mucus-degrading …
direct contact with intestinal microbes but also constitutes a substrate for mucus-degrading …
Microbiome and food allergy
AB Blázquez, MC Berin - Translational Research, 2017 - Elsevier
Food allergy is a common disease affecting approximately 8% of children and 5% of adults.
The prevalence has increased over the last two decades, suggesting an important …
The prevalence has increased over the last two decades, suggesting an important …
Antibiotic-induced gut microbiota dysbiosis damages the intestinal barrier, increasing food allergy in adult mice
Q Zhang, L Cheng, J Wang, M Hao, H Che - Nutrients, 2021 - mdpi.com
(1) Background: The use of antibiotics affects the composition of gut microbiota. Studies
have suggested that the colonization of gut microbiota in early life is related to later food …
have suggested that the colonization of gut microbiota in early life is related to later food …
Akkermansia muciniphila mediates negative effects of IFNγ on glucose metabolism
RL Greer, X Dong, ACF Moraes, RA Zielke… - Nature …, 2016 - nature.com
Cross-talk between the gut microbiota and the host immune system regulates host
metabolism, and its dysregulation can cause metabolic disease. Here, we show that the gut …
metabolism, and its dysregulation can cause metabolic disease. Here, we show that the gut …
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and
gut barrier disruption. Microbial composition and the mechanisms of interaction with the host …
gut barrier disruption. Microbial composition and the mechanisms of interaction with the host …
Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice
A Hänninen, R Toivonen, S Pöysti, C Belzer, H Plovier… - Gut, 2018 - gut.bmj.com
Objective Intestinal microbiota is implicated in the pathogenesis of autoimmune type 1
diabetes in humans and in non-obese diabetic (NOD) mice, but evidence on its causality …
diabetes in humans and in non-obese diabetic (NOD) mice, but evidence on its causality …
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