Glaucoma: neuroprotection with NAD-based therapeutic interventions
A Chiarugi - Trends in Pharmacological Sciences, 2023 - cell.com
Clinical evidence shows that intraocular hypertension is not the primary pathogenetic event
of glaucoma, whereas early neurodegeneration of retinal ganglion cells (RGCs) represents …
of glaucoma, whereas early neurodegeneration of retinal ganglion cells (RGCs) represents …
Systemic treatment with nicotinamide riboside is protective in two mouse models of retinal ganglion cell damage
Glaucoma etiology often includes retinal ganglion cell (RGC) death associated with elevated
intraocular pressure (IOP). However, even when IOP is managed well, disease can …
intraocular pressure (IOP). However, even when IOP is managed well, disease can …
Neuroprotection in glaucoma: drug-based approaches
W Cheung, L Guo, MF Cordeiro - Optometry and Vision Science, 2008 - journals.lww.com
In recent years the focus of glaucoma research has shifted toward neuroprotection, as the
traditional strategies of lowering intraocular pressure have been shown to be unable to …
traditional strategies of lowering intraocular pressure have been shown to be unable to …
[HTML][HTML] Neuroprotective strategies in glaucoma-translation to clinical trials
Neuroprotection in glaucoma is any medical treatment by which decline in visual function
can be slowed or prevented by supporting the health and survival of neural cells …
can be slowed or prevented by supporting the health and survival of neural cells …
Neuroprotective strategies in glaucoma
CA Gossman, J Christie, MK Webster… - Current …, 2016 - ingentaconnect.com
Background: Glaucoma is characterized as a neuropathic disease that causes progressive
degeneration of retinal ganglion cells (RGCs) in the retina, resulting in irreversible loss of …
degeneration of retinal ganglion cells (RGCs) in the retina, resulting in irreversible loss of …
Neuroprotective agents in the management of glaucoma
Glaucoma is an optic neuropathy, specifically a neurodegenerative disease characterized
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects
A Boccaccini, D Cavaterra, C Carnevale… - Molecular Aspects of …, 2023 - Elsevier
In the last years, neuroprotective therapies have attracted the researcher interests as
modern and challenging approach for the treatment of neurodegenerative diseases, aimed …
modern and challenging approach for the treatment of neurodegenerative diseases, aimed …
Current perspective of neuroprotection and glaucoma
K Tian, S Shibata-Germanos, M Pahlitzsch… - Clinical …, 2015 - Taylor & Francis
Glaucoma is the second leading cause of blindness worldwide and is most notably
characterized by progressive optic nerve atrophy and advancing loss of retinal ganglion …
characterized by progressive optic nerve atrophy and advancing loss of retinal ganglion …
Rationale for the use of multifunctional drugs as neuroprotective agents for glaucoma☆
J Fang, F Jiang, J Li, Y Zhu - Neural Regeneration Research, 2012 - journals.lww.com
Glaucoma, the leading cause globally of irreversible blindness, is a neurodegenerative
disease characterized by progressive retinal ganglion cell death. To date, no drug has been …
disease characterized by progressive retinal ganglion cell death. To date, no drug has been …
Targets of neuroprotection in glaucoma
S He, DL Stankowska, DZ Ellis… - Journal of Ocular …, 2018 - liebertpub.com
Progressive neurodegeneration of the optic nerve and the loss of retinal ganglion cells is a
hallmark of glaucoma, the leading cause of irreversible blindness worldwide, with primary …
hallmark of glaucoma, the leading cause of irreversible blindness worldwide, with primary …