[HTML][HTML] Genome-wide DNA methylation profiling after Ayurveda intervention to bronchial asthmatics identifies differential methylation in several transcription factors …

S Bhat, H Rotti, K Prasad, SP Kabekkodu… - Journal of Ayurveda and …, 2023 - Elsevier
Abstract Background The Indian traditional medicinal system, Ayurveda, describes several
lifestyle practices, processes and medicines as an intervention to treat asthma. Rasayana …

Integrative analysis identifies gene signatures mediating the effect of DNA methylation on asthma severity and lung function

EY Dessie, L Ding, TB Mersha - Clinical Epigenetics, 2024 - Springer
DNA methylation (DNAm) changes play a key role in regulating gene expression in asthma.
To investigate the role of epigenetics and transcriptomics change in asthma, we used …

Genome‑wide analysis of DNA methylation and gene expression changes in an ovalbumin‑induced asthma mouse model

JS Kim, IS Shin, NR Shin… - Molecular medicine …, 2020 - spandidos-publications.com
The aim of the present study was to establish an integrated network of DNA methylation and
RNA expression in an ovalbumin (OVA)‑induced asthma model, and to investigate the …

Epigenome-wide association study identifies DNA methylation markers for asthma remission in whole blood and nasal epithelium

C Qi, JM Vonk, DA van der Plaat… - Clinical and translational …, 2020 - Springer
Background Asthma is a chronic respiratory disease which is not curable, yet some patients
experience spontaneous remission. We hypothesized that epigenetic mechanisms may be …

Differences in the DNA Methylome of T cells in Adults With Asthma of Varying Severity

Y Liao, R Cavalcante, J Waller, F Deng, A Scruggs… - 2024 - researchsquare.com
Background DNA methylation plays a critical role in asthma development, but differences in
DNA methylation among adults with varying asthma severity or asthma endotypes are less …

Genome-wide methylation profiling of the bronchial mucosa of asthmatics: relationship to atopy

YJ Kim, SW Park, TH Kim, JS Park, HS Cheong… - BMC medical …, 2013 - Springer
Background Asthma is a common respiratory disease that is characterized by bronchial
hyperresponsiveness and airway obstruction due to chronic airway inflammation. Atopic …

Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma

K Recto, P Kachroo, T Huan, D Van Den Berg… - …, 2023 - thelancet.com
Background Identifying novel epigenetic signatures associated with serum immunoglobulin
E (IgE) may improve our understanding of molecular mechanisms underlying asthma and …

The landscape of DNA methylation in asthma: a data mining and validation

H Yang, F Na, L Guo, X Liang, RF Zhang - Bioengineered, 2021 - Taylor & Francis
Human asthma is caused by interactions between a range of genetic and environmental
factors. However, the specific pathogenesis of asthma remains controversial. This study …

Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma

D Rastogi, M Suzuki, JM Greally - Scientific reports, 2013 - nature.com
While DNA methylation plays a role in T-helper (Th) cell maturation, its potential
dysregulation in the non-atopic Th1-polarized systemic inflammation observed in obesity …

Identification of candidate aberrant differentially methylated/expressed genes in asthma

Z Wang, L Wang, L Dai, Y Wang, E Li, S An… - Allergy, Asthma & …, 2022 - Springer
Background Asthma is an important non-communicable disease worldwide. DNA
methylation is associated with the occurrence and development of asthma. We are aimed at …