[HTML][HTML] The future of clinical phage therapy in the United Kingdom

JD Jones, C Trippett, M Suleman, MRJ Clokie, JR Clark - Viruses, 2023 - mdpi.com
Bacteriophage (phage) therapy is a promising alternative antimicrobial strategy with the
potential to transform the way bacterial infections are treated. In the United Kingdom, phages …

Clinical application of bacteriophages in Europe

JP Pirnay, D De Vos, G Verbeken - Microbiology Australia, 2019 - CSIRO Publishing
Bacteriophages could help address the antibiotic resistance crisis that impacts health
systems all over the world. In 2011, the European Commission formally confirmed that …

[HTML][HTML] Phage therapy for severe bacterial infections: a narrative review

AP Fabijan, A Khalid, S Maddocks, J Ho… - The Medical Journal …, 2020 - ncbi.nlm.nih.gov
• Activity against antibiotic-resistant pathogens and a lack of serious side effects make
phage therapy an attractive treatment option in refractory bacterial infections.• Phages are …

[HTML][HTML] Phage therapy in Germany—update 2023

C Willy, JJ Bugert, AY Classen, L Deng, A Düchting… - Viruses, 2023 - mdpi.com
Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally
and in Germany. Here, we provide an overview of the current situation (2023) of applied …

[HTML][HTML] A wake-up call: we need phage therapy now

K Moelling, F Broecker, C Willy - Viruses, 2018 - mdpi.com
The rise of multidrug-resistant bacteria has resulted in an increased interest in phage
therapy, which historically preceded antibiotic treatment against bacterial infections. To date …

What are the limitations on the wider therapeutic use of phage?

A Henein - Bacteriophage, 2013 - Taylor & Francis
Bacterial resistance to antibiotics poses a serious health threat. Since research into new
antibiotics is not progressing at the same rate as the development of bacterial resistance …

[HTML][HTML] Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

[HTML][HTML] Bacteriophage Therapy for Difficult-to-Treat Infections: The Implementation of a Multidisciplinary Phage Task Force (The PHAGEFORCE Study Protocol)

J Onsea, S Uyttebroek, B Chen, J Wagemans, C Lood… - Viruses, 2021 - mdpi.com
In times where only a few novel antibiotics are to be expected, antimicrobial resistance
remains an expanding global health threat. In case of chronic infections caused by therapy …

Phage therapy: delivering on the promise

DR Harper, J Anderson, MC Enright - Therapeutic delivery, 2011 - Taylor & Francis
Bacteriophages are viruses that infect and, in many cases, destroy their bacterial targets.
Within a few years of their initial discovery they were being investigated as therapeutic …

[HTML][HTML] A phage therapy guide for clinicians and basic scientists: background and highlighting applications for developing countries

A Khalid, RCY Lin, JR Iredell - Frontiers in Microbiology, 2021 - frontiersin.org
Approximately 10% of global health research is devoted to 90% of global disease burden
(the so-called “10/90 Gap”) and it often neglects those diseases most prevalent in low …