In human diseases associated with G protein, changes in abnormal content and distribution
of multiple signalingmolecules and abnormal signaling pathways play critical roles in …

Cell signaling is a fundamental process that enables cells to survive under various
ecological and environmental contexts and imparts tolerance towards stressful conditions …

G-proteins and G-proteins receptors play an extremely important role in the physiological
functions of the human body and various cells. They are closely related to tumors and …

Over the past three decades, after Nobel prizes, Robert Lefkowitz and Brian Kobilka
characterized G protein-coupled receptors (GPCRs) structure [1], several clinical and …

The regulation of human development, responsiveness to environmental signals, and
coordination of cellular growth and function require intercellular communication mediated by …

G-protein coupled receptor is a type of cell membrane receptor that plays a crucial role in
cellular signaling and is involved in various physiological processes in the human body …

Background Many marketed therapeutic agents have been developed to modulate the
function of G protein-coupled receptors (GPCRs). The regulators of G-protein signaling …

G protein-coupled receptors (GPCRs) play a major role in signal transduction and are
targets of many therapeutic drugs. The regulator of G protein signaling (RGS) proteins form a …

Background Understanding the mechanisms, activated and inhibited pathways as well as
other molecular targets involved in existing and emerging disease conditions provides …

Cell signaling plays critical role in health and disease. The normal functioning of body
depends on the homeostasis of immunity players. One of the very important cell signaling …