Context Atherosclerosis is a systemic pro-inflammatory and pro-oxidative disease,
accounting for approximately a third of deaths globally. It has been proposed that omega-3s …

Background: Uncertainty exists about the link between omega-3 fatty acid, omega-6 fatty
acid, and total polyunsaturated fatty acid (PUFA) intake and mortality in atherosclerotic …

Background Although omega-3 fatty acids have well documented properties which would
reduce the cardiovascular (CV) disease risk, the evidence from randomized controlled trials …

Background Multiple randomized controlled trials (RCTs) have examined the cardiovascular
effects of omega-3 fatty acids and have provided unexplained conflicting results. A meta …

Introduction: Cardiovascular disease remains the commonest health problem in developed
countries, and residual risk after implementing all current therapies is still high. The use of …

Importance Current guidelines advocate the use of marine-derived omega-3 fatty acids
supplements for the prevention of coronary heart disease and major vascular events in …

Omega-3 supplementation has a controversial role in the secondary prevention of
cardiovascular diseases. Despite large clinical trials published over the years, the evidence …

Several studies and reviews regarding the supplementation of omega-3 LC-PUFAs have
been developed during the last years. Indeed, the evidence states that high doses omega-3 …

Background Epidemiologic data suggest that omega‐3 fatty acids derived from fish oil
reduce cardiovascular disease. The clinical benefit of dietary fish oil supplementation in …

Introduction: Large-scale epidemiological studies on Greenlandic, Canadian and Alaskan
Eskimos have examined the health benefits of omega-3 fatty acids consumed as part of the …