Clonal hematopoiesis of indeterminate potential is rare in pediatric patients undergoing autologous stem cell transplantation
M Kartal-Kaess, A Karow, U Bacher… - Pediatric hematology …, 2024 - Taylor & Francis
Clonal hematopoiesis of indeterminate potential (CHIP) describes recurrent somatic gene
mutations in the blood of healthy individuals, associated with higher risk for hematological …
mutations in the blood of healthy individuals, associated with higher risk for hematological …
Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study
NP Tjader, AJ Beer, J Ramroop, MC Tai… - Cancer research …, 2024 - aacrjournals.org
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype
and ancestry. Emerging data suggest tumor mutation status is associated with germline …
and ancestry. Emerging data suggest tumor mutation status is associated with germline …
[PDF][PDF] TP53 突变在前列腺癌发生发展以及治疗与预后评估中作用的研究进展
汪正斌， 温诚浩， 张力 - 临床泌尿外科杂志, 2024 - lcmw.whuhzzs.com
前列腺癌(prostatecancer, PCa) 是男性泌尿生殖系最常见的恶性肿瘤之一,
其发病率及死亡率近年来逐渐升高. 研究表明肿瘤抑制基因TP53 突变在PCa 中起着重要作用 …
其发病率及死亡率近年来逐渐升高. 研究表明肿瘤抑制基因TP53 突变在PCa 中起着重要作用 …
[HTML][HTML] Significance of RCC2, Rac1 and p53 Expression in Breast Infiltrating Ductal Carcinoma; An Immunohistochemical Study
AS Hemida, RA Abdelaziz… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Methods: Immunostaining was performed on 120 breast IDC specimens using RCC2, Rac1,
and p53 antibodies. Statistical analyses were conducted to examine the correlations …
and p53 antibodies. Statistical analyses were conducted to examine the correlations …
TP53 Y220C mutations in patients with myeloid malignancies
G Gener-Ricos, JP Bewersdorf, S Loghavi… - Leukemia & …, 2024 - Taylor & Francis
2 Letter to the editor (32–91), and 82 (59%) were male. Most patients had a diagnosis of
MdS (n= 73) or AML (n= 58) at the time of Y220C detection, and 64% were newly diagnosed …
MdS (n= 73) or AML (n= 58) at the time of Y220C detection, and 64% were newly diagnosed …
[HTML][HTML] 宫颈癌的临床病理研究进展
陈丽鹃， 华媛媛 - Advances in Clinical Medicine, 2024 - hanspub.org
宫颈癌是全球各国中妇女发病率和死亡率最高的恶性肿瘤之一. 近些年, 宫颈癌的患病年龄呈现
出年轻化的趋势. 近期发现的Silva 分型相比于目前的传统诊断依据, 可更有效地预见宫颈腺癌的 …
出年轻化的趋势. 近期发现的Silva 分型相比于目前的传统诊断依据, 可更有效地预见宫颈腺癌的 …
Malignant epithelial neoplasms of the large intestine
SV Walsh, K Sheahan, FA Carey - Morson and Dawson's …, 2024 - Wiley Online Library
Adenocarcinomas of the large bowel are among the most common human malignancies.
This chapter discusses the epidemiology and pathogenesis of large‐bowel cancer. It …
This chapter discusses the epidemiology and pathogenesis of large‐bowel cancer. It …
Adrenal cortical carcinoma: Paediatric aspects–literature review
P Dasiewicz, E Moszczyńska… - … Diabetes and Metabolism, 2024 - termedia.pl
Results Most cases of ACC in children occur under the age of 5 years. The most common
presenting symptom in 60–80% of paediatric patients is rapidly progressive virilisation …
presenting symptom in 60–80% of paediatric patients is rapidly progressive virilisation …
Effect of C-to-T transition at CpG sites on tumor suppressor genes in tumor development in cattle evaluated by somatic mutation analysis in enzootic bovine leukosis
Oncogenic transformation of normal cells is caused by mutations and chromosomal
abnormalities in cancer-related genes. Enzootic bovine leukosis (EBL) is a malignant B-cell …
abnormalities in cancer-related genes. Enzootic bovine leukosis (EBL) is a malignant B-cell …
Safety Issues Related to Pluripotent Stem Cell-Based Therapies: Tumour Risk
S Hillenius, J Montilla-Rojo, TF Eleveld… - Pluripotent Stem Cell …, 2024 - Springer
As the exciting era of regenerative medicine has dawned, considerable efforts aim to further
develop human pluripotent stem cell (hPSC)-based therapies for a plethora of diseases …
develop human pluripotent stem cell (hPSC)-based therapies for a plethora of diseases …