Identification of long noncoding RNAs downregulated specifically in ovarian high‐grade serous carcinoma

M Hayashi‐Okada, S Sato, K Nakashima… - Reproductive …, 2024 - Wiley Online Library
Purpose To investigate whether long noncoding RNAs (lncRNAs) are involved in the
development or malignant behavior of ovarian high‐grade serous carcinoma (HGSC), we …

DMLS: an automated pipeline to extract the Drosophila modular transcription regulators and targets from massive literature articles

TH Yang, YH Yu, SH Wu, FY Chang, HC Tsai… - Database, 2024 - academic.oup.com
Transcription regulation in multicellular species is mediated by modular transcription factor
(TF) binding site combinations termed cis-regulatory modules (CRMs). Such CRM-mediated …

LncRNA-PCat19 acts as a ceRNA of miR-378a-3p to facilitate microglia activation and accelerate chronic neuropathic pain in rats by promoting KDM3A-mediated …

Z Zhao, X Zheng, H Wang, J Guo, R Liu, G Yang… - Molecular …, 2024 - Elsevier
The pathogenesis of neuropathic pain (NP) is complex, and there are various pathological
processes. Previous studies have suggested that lncRNA PCAT19 is abnormally expressed …

Susceptibility of TSPAN5 polymorphisms to Kawasaki disease and immunoglobulin therapy resistance in southern Chinese children

K Chen, X Luo, H Zhou, L Fu, Z Lu, C Wang, Y Lin… - Heliyon, 2024 - cell.com
Kawasaki disease (KD) is a condition characterized by acute multi-system vasculitis and
high fever in infants and children. Intravenous immunoglobulin (IVIG) is the established …

Functional SNPs in SYISL promoter significantly affect muscle fiber density and muscle traits in pigs

W Lv, Y Peng, J Hu, M Zhu, Y Mao, L Wang… - Animal …, 2024 - Wiley Online Library
Our previous studies showed that SYISL is a negative regulator of muscle growth and
regeneration in mice, pigs and humans. SYISL knockout resulted in an increase in the …

LncCE: Landscape of Cellular-Elevated LncRNAs in Single Cells Across Normal and Cancer Tissues

K Xu, Y Liu, C Lv, Y Luo, J Shi, H Zou, W Zhou, D Lv… - bioRxiv, 2024 - biorxiv.org
Long non-coding RNAs (lncRNAs) have emerged as significant players for maintaining the
morphology and function of tissues or cells. The precise regulatory effectiveness of lncRNA …

Epigenetic Control of Cell Fate Decisions by Enhancer-Derived Long Noncoding RNAs

JS Mattick - Epigenetics in Biological Communication, 2024 - Springer
The development of mammals from conception to adult involves trillions of cell fate decisions
that must be made with 4-dimensional precision to form the myriad of architecturally sculpted …

Genetic Susceptibility to Prostate Cancer

T Simic, M Matic, D Jerotic - Prostate Cancer: Advancements in the …, 2024 - Springer
Prostate cancer (PCa) is the second most diagnosed cancer type globally and is one of the
leading causes of death in men. Genetic susceptibility plays a significant role in PCa …

Classification of Single-Nucleotide Polymorphisms (SNPs): Tips from the Basic Knowledge to the Clinical Outcomes

MBS Al-Shuhaib - 2024 - Springer
Single-nucleotide polymorphisms (SNPs) are the cornerstone of individuals' variations in
sensitivity to cancer and drugs. The necessity of understanding how SNPs work is an urgent …

LncRNA FAM83H-AS1 Contributes to the Radio-resistance and Proliferation in Liver Cancer through Stability FAM83H Protein

X Jiang, Y Lan, Y Zhang, Y Dong… - Recent Patents on Anti …, 2024 - ingentaconnect.com
Background: Liver cancer (LC) is one of China's most common malignant tumors, with a high
mortality rate, ranking third leading cause of death after gastric and esophageal cancer …