[HTML][HTML] Transportation Engineering for Enhanced Production of Plant Natural Products in Microbial Cell Factories

Y Zuo, M Zhao, Y Gou, L Huang, Z Xu, J Lian - Synthetic and Systems …, 2024 - Elsevier
Plant natural products (PNPs) exhibit a wide range of biological activities and have essential
applications in various fields such as medicine, agriculture, and flavors. Given their natural …

Transporter and its engineering for secondary metabolites

H Lv, J Li, Y Wu, S Garyali, Y Wang - Applied microbiology and …, 2016 - Springer
Secondary metabolites possess a lot of biological activities, and to achieve their functions,
transmembrane transportation is crucial. Elucidation of their transport mechanisms in the cell …

Engineering microbial cell factories for the production of plant natural products: from design principles to industrial-scale production

X Liu, W Ding, H Jiang - Microbial cell factories, 2017 - Springer
Plant natural products (PNPs) are widely used as pharmaceuticals, nutraceuticals,
seasonings, pigments, etc., with a huge commercial value on the global market. However …

Transporter engineering in microbial cell factory boosts biomanufacturing capacity

X Lv, H Xue, L Qin, C Li - BioDesign Research, 2022 - spj.science.org
Microbial cell factories (MCFs) are typical and widely used platforms in biomanufacturing for
designing and constructing synthesis pathways of target compounds in microorganisms. In …

Transporter engineering for microbial manufacturing

Y Zhu, C Zhou, Y Wang, C Li - Biotechnology Journal, 2020 - Wiley Online Library
Microbes play an important role in biotransformation and biosynthesis of biofuels, natural
products, and polymers. Therefore, microbial manufacturing has been widely used in …

[HTML][HTML] Transport engineering in microbial cell factories producing plant-specialized metabolites

ZM Belew, M Poborsky, HH Nour-Eldin… - Current Opinion in Green …, 2022 - Elsevier
Transport engineering strategies use altered expression of transporter proteins to change
metabolite distribution within an organism. The production of plant specialized metabolites …

Multiscale and multidisciplinary approach to understanding nanoparticle transport in plants

JD Hubbard, A Lui, MP Landry - Current Opinion in Chemical Engineering, 2020 - Elsevier
Recent advances in nanoparticle (NP) technology have revealed potential to improve
efficiencies in agriculture and plant biotechnology—specifically through controlled nutrient …

Transcending membrane barriers: advances in membrane engineering to enhance the production capacity of microbial cell factories

T Wu, J Jiang, H Zhang, J Liu, H Ruan - Microbial Cell Factories, 2024 - Springer
Microbial cell factories serve as pivotal platforms for the production of high-value natural
products, which tend to accumulate on the cell membrane due to their hydrophobic …

Compartmentalization and transporter engineering strategies for terpenoid synthesis

K Jin, H Xia, Y Liu, J Li, G Du, X Lv, L Liu - Microbial Cell Factories, 2022 - Springer
Microbial cell factories for terpenoid synthesis form a less expensive and more environment-
friendly approach than chemical synthesis and extraction, and are thus being regarded as …

[HTML][HTML] Transporter engineering in microbial cell factories: the ins, the outs, and the in-betweens

SA van der Hoek, I Borodina - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Transporter proteins are essential for substrate uptake, product export, and
intercompartmental metabolite exchange.•Transporter activity of a cell can be engineered to …