Current understanding of the molecular mechanisms of chemotherapy-induced peripheral neuropathy

X Chen, Y Gan, NPB Au, CHE Ma - Frontiers in Molecular …, 2024 - frontiersin.org
Chemotherapy-induced peripheral neuropathy (CIPN) is the most common off-target
adverse effects caused by various chemotherapeutic agents, such as cisplatin, oxaliplatin …

[HTML][HTML] A mechanistic understanding of axon degeneration in chemotherapy-induced peripheral neuropathy

Y Fukuda, Y Li, RA Segal - Frontiers in neuroscience, 2017 - frontiersin.org
Chemotherapeutic agents cause many short and long term toxic side effects to peripheral
nervous system (PNS) that drastically alter quality of life. Chemotherapy-induced peripheral …

[HTML][HTML] Molecular and Cellular Involvement in CIPN

H Kacem, A Cimini, M d'Angelo, V Castelli - Biomedicines, 2024 - mdpi.com
Many anti-cancer drugs, such as taxanes, platinum compounds, vinca alkaloids, and
proteasome inhibitors, can cause chemotherapy-induced peripheral neuropathy (CIPN) …

[HTML][HTML] Integrated medicine for chemotherapy-induced peripheral neuropathy

CH Tsai, YH Lin, YS Li, TL Ho, LH Hoai Thuong… - International Journal of …, 2021 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of typical
chemotherapeutics among cancer survivors. Despite the recent progress, the effective …

A comparative review of chemotherapy-induced peripheral neuropathy in in vivo and in vitro models

S Eldridge, L Guo, J Hamre III - Toxicologic pathology, 2020 - journals.sagepub.com
Chemotherapy-induced peripheral neuropathy (CIPN) is an adverse effect caused by
several classes of widely used anticancer therapeutics. Chemotherapy-induced peripheral …

[HTML][HTML] Review of the role of the brain in chemotherapy-induced peripheral neuropathy

M Omran, EK Belcher, NA Mohile, SR Kesler… - Frontiers in Molecular …, 2021 - frontiersin.org
Chemotherapy-induced peripheral neuropathy (CIPN) is a common, debilitating, and dose-
limiting side effect of many chemotherapy regimens yet has limited treatments due to …

[HTML][HTML] Chemotherapy-induced peripheral neuropathy: mechanisms and therapeutic avenues

EH Bae, MK Greenwald, AG Schwartz - Neurotherapeutics, 2021 - Elsevier
Chemotherapy-induced peripheral neuropathy (CIPN) is a serious and often persistent
adverse consequence of certain chemotherapeutic agents. It is a major dose-limiting factor …

Prevention and treatment for chemotherapy-induced peripheral neuropathy: therapies based on CIPN mechanisms

LY Hu, WL Mi, GC Wu, YQ Wang… - Current …, 2019 - ingentaconnect.com
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive,
enduring, and often irreversible adverse effect of many antineoplastic agents, among which …

[HTML][HTML] Long-term effects, pathophysiological mechanisms, and risk factors of chemotherapy-induced peripheral neuropathies: a comprehensive literature review

N Kerckhove, A Collin, S Condé, C Chaleteix… - Frontiers in …, 2017 - frontiersin.org
Neurotoxic anticancer drugs, such as platinum-based anticancer drugs, taxanes, vinca
alkaloids, and proteasome/angiogenesis inhibitors are responsible for chemotherapy …

[HTML][HTML] Chemotherapy-Induced Peripheral Neuropathy: A Recent Update on Pathophysiology and Treatment

M Mattar, F Umutoni, MA Hassan, MW Wamburu… - Life, 2024 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a major long-lasting side effect of
some chemotherapy drugs, which threatens cancer survival rate. CIPN mostly affects …