The prevalence of myopia (nearsightedness) is increasing to alarming levels, but its etiology
remains poorly understood. Because both laboratory and clinical findings suggest an …

Purpose: Stimulated by evidence implicating diurnal/circadian rhythms and light in refractive
development, we studied the expression over 24 hours of selected clock and circadian …

Myopia, a common ophthalmic disorder, places a high economic burden on individuals and
society. Genetic and environmental factors influence myopia progression; however, the …

The pathophysiology of refractive errors is poorly understood. Myopia (nearsightedness) in
particular both blurs vision and predisposes the eye to many blinding diseases during …

Despite the high prevalence and public health impact of refractive errors, the mechanisms
responsible for ametropias are poorly understood. Much evidence now supports the concept …

Myopia is the most common eye disorder, caused by heterogeneous genetic and
environmental factors. Rare progressive and stationary inherited retinal disorders are often …

Purpose Despite extensive research, mechanisms regulating postnatal eye growth and
those responsible for ametropias are poorly understood. With the marked recent increases …

Myopia has been investigated scientifically for over a century but the search for an effective
remedy has been manifestly unsuccessful. The prevalence of myopia in developed societies …

Various studies have suggested several environmental, pharmacological, medical, and
optical interventions and some are in use but their efficacy in myopia control may be …

Purpose: To identify commonalities between the genes in close proximity to genome-wide
association study (GWAS) refractive error and axial length loci, and the genes and proteins …