Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders

C Mu, X Dang, XJ Luo - Nature human behaviour, 2024 - nature.com
Dysfunction of brain resting-state functional networks has been widely reported in
psychiatric disorders. However, the causal relationships between brain resting-state …

Establishing the resting state default mode network derived from functional magnetic resonance imaging tasks as an endophenotype: a twins study

MS Korgaonkar, K Ram, LM Williams… - Human brain …, 2014 - Wiley Online Library
The resting state default mode network (DMN) has been shown to characterize a number of
neurological and psychiatric disorders. Evidence suggests an underlying genetic basis for …

Common dysfunction of large-scale neurocognitive networks across psychiatric disorders

Z Sha, TD Wager, A Mechelli, Y He - Biological psychiatry, 2019 - Elsevier
Background Cognitive dysfunction is one of the most prominent characteristics of psychiatric
disorders. Currently, the neural correlates of cognitive dysfunction across psychiatric …

Genetic influences on resting‐state functional networks: A twin study

Y Fu, Z Ma, C Hamilton, Z Liang, X Hou… - Human brain …, 2015 - Wiley Online Library
Alterations in resting‐state networks (RSNs) are often associated with psychiatric and
neurologic disorders. Given this critical linkage, it has been hypothesized that RSNs can …

[HTML][HTML] Mendelian randomization studies of brain MRI yield insights into the pathogenesis of neuropsychiatric disorders

W Song, W Qian, W Wang, S Yu, GN Lin - BMC genomics, 2021 - Springer
Background Observational studies have identified various associations between
neuroimaging alterations and neuropsychiatric disorders. However, whether such …

[HTML][HTML] Convergent and divergent functional connectivity patterns in schizophrenia and depression

Y Yu, H Shen, LL Zeng, Q Ma, D Hu - PLoS One, 2013 - journals.plos.org
Major depression and schizophrenia are two of the most serious psychiatric disorders and
share similar behavioral symptoms. Whether these similar behavioral symptoms underlie …

[HTML][HTML] Transdiagnostic connectome signatures from resting-state fMRI predict individual-level intellectual capacity

X Tong, H Xie, N Carlisle, GA Fonzo, DJ Oathes… - Translational …, 2022 - nature.com
Medication and other therapies for psychiatric disorders show unsatisfying efficacy, in part
due to the significant clinical/biological heterogeneity within each disorder and our over …

[HTML][HTML] Brain networks and cognitive impairment in psychiatric disorders

V Menon - World Psychiatry, 2020 - ncbi.nlm.nih.gov
Cognitive impairments are a prominent feature of all psychiatric disorders. The goal of
mapping each disorder to individual brain areas has now been largely abandoned, and …

[HTML][HTML] Resting-state time-varying analysis reveals aberrant variations of functional connectivity in autism

Z Yao, B Hu, Y Xie, F Zheng, G Liu, X Chen… - Frontiers in human …, 2016 - frontiersin.org
Recently, studies based on time-varying functional connectivity have unveiled brain states
diversity in some neuropsychiatric disorders, such as schizophrenia and major depressive …

[HTML][HTML] Variability in resting state network and functional network connectivity associated with schizophrenia genetic risk: a pilot study

J Chen, B Rashid, Q Yu, J Liu, D Lin, Y Du… - Frontiers in …, 2018 - frontiersin.org
Imaging genetics posits a valuable strategy for elucidating genetic influences on brain
abnormalities in psychiatric disorders. However, association analysis between 2D genetic …