The Roles of RhoA/ROCK/NF-κB Pathway in Microglia Polarization Following Ischemic Stroke
W Lu, Y Wang, J Wen - Journal of Neuroimmune Pharmacology, 2024 - Springer
Ischemic stroke is the leading cause of death and disability worldwide. Nevertheless, there
still lacks the effective therapies for ischemic stroke. Microglia are resident macrophages of …
still lacks the effective therapies for ischemic stroke. Microglia are resident macrophages of …
[HTML][HTML] Effects of microglial activation and polarization on brain injury after stroke
R Dong, R Huang, J Wang, H Liu, Z Xu - Frontiers in neurology, 2021 - frontiersin.org
Stroke is one of the most common causes of death worldwide. The subsequent development
of neuroinflammation and brain edema dramatically increases the risks associated with …
of neuroinflammation and brain edema dramatically increases the risks associated with …
[HTML][HTML] The dual function of microglial polarization and its treatment targets in ischemic stroke
Y Mo, W Xu, K Fu, H Chen, J Wen, Q Huang… - Frontiers in …, 2022 - frontiersin.org
Stroke is the leading cause of disability and death worldwide, with ischemic stroke occurring
in~ 5% of the global population every year. Recently, many studies have been conducted on …
in~ 5% of the global population every year. Recently, many studies have been conducted on …
[HTML][HTML] The role of RhoA/ROCK pathway in the ischemic stroke-induced neuroinflammation
W Lu, Z Chen, J Wen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
It is widely known that ischemic stroke is the prominent cause of death and disability. To
date, neuroinflammation following ischemic stroke represents a complex event, which is an …
date, neuroinflammation following ischemic stroke represents a complex event, which is an …
Microglia in Ischemic Stroke: Pathogenesis Insights and Therapeutic Challenges
X Shui, J Chen, Z Fu, H Zhu, H Tao… - Journal of Inflammation …, 2024 - Taylor & Francis
Ischemic stroke is the most common type of stroke, which is the main cause of death and
disability on a global scale. As the primary immune cells in the brain that are crucial for …
disability on a global scale. As the primary immune cells in the brain that are crucial for …
Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia
X Gao, G Su, M Chai, M Shen, Z Hu, W Chen… - Neurochemistry …, 2023 - Elsevier
Microglia, as the intrinsic immune cells in the brain, are activated following ischemic stroke.
Activated microglia participate in the pathological processes after stroke through …
Activated microglia participate in the pathological processes after stroke through …
[HTML][HTML] Regulation of microglia polarization after cerebral ischemia
H Wang, J Li, H Zhang, M Wang, L Xiao… - Frontiers in Cellular …, 2023 - frontiersin.org
Stroke ranks second as a leading cause of death and permanent disability globally.
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …
[HTML][HTML] Modulators of microglia activation and polarization in ischemic stroke
CT Jiang, WF Wu, YH Deng… - Molecular medicine …, 2020 - spandidos-publications.com
Ischemic stroke is one of the leading causes of mortality and disability worldwide. However,
there is a current lack of effective therapies available. As the resident macrophages of the …
there is a current lack of effective therapies available. As the resident macrophages of the …
Polarization of microglia/macrophages and its role in ischemic stroke repair
T ZHU - Chinese Pharmacological Bulletin, 2019 - pesquisa.bvsalud.org
Traditionally, microglia/macrophage activation is thought to be detrimental in ischemic
stroke. However, there is increasing evidence that microglia/macrophage activation is …
stroke. However, there is increasing evidence that microglia/macrophage activation is …
[HTML][HTML] Microglia and monocytes/macrophages polarization reveal novel therapeutic mechanism against stroke
M Kanazawa, I Ninomiya, M Hatakeyama… - International journal of …, 2017 - mdpi.com
Stroke is a leading cause of morbidity and mortality worldwide, and consists of two types,
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …
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