[HTML][HTML] Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic …

L Veletzky, KA Eberhardt, J Hergeth… - PLOS Neglected …, 2024 - journals.plos.org
Background The parasitic disease loiasis is associated with significant morbidity and
mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of …

Profile of loiasis infection through clinical and laboratory diagnostics: the importance of biomarkers

R Dieki, ER Eyang Assengone… - Transactions of The …, 2023 - academic.oup.com
ABSTRACT Background Detection of Loa loa microfilariae in peripheral blood is insensitive
given only 30% of individuals are microfilaraemic while 70% are amicrofilaraemic with a …

[HTML][HTML] Performance of two serodiagnostic tests for loiasis in a non-endemic area

F Gobbi, D Buonfrate, M Boussinesq… - PLoS Neglected …, 2020 - journals.plos.org
Loiasis, caused by the filarial nematode Loa loa, is endemic in Central and West Africa
where about 10 million people are infected. There is a scarcity of convenient, commercial …

[HTML][HTML] Rapid Molecular Assays for Specific Detection and Quantitation of Loa loa Microfilaremia

DL Fink, J Kamgno, TB Nutman - PLoS neglected tropical …, 2011 - journals.plos.org
Background Accurate diagnosis of Loa loa infection is essential to the success of mass drug
administration efforts to eliminate onchocerciasis and lymphatic filariasis, due to the risk of …

Excess mortality associated with loiasis: a retrospective population-based cohort study

CB Chesnais, I Takougang, M Paguélé… - The Lancet Infectious …, 2017 - thelancet.com
Background The burden of loiasis has received limited attention and loiasis is still
considered a benign condition. To assess whether loiasis bears any excess mortality, we did …

Excess mortality associated with loiasis: confirmation by a new retrospective cohort study conducted in the Republic of Congo

MC Hemilembolo, AC Niama… - Open Forum …, 2023 - academic.oup.com
Abstract Background Loiasis (Loa loa filariasis) is considered a benign disease and is
currently not included in the World Health Organization's (WHO's) list of Neglected Tropical …

New promising method to assess microfilarial Loa loa load on the peripheral blood

O Mouri, N Ezzine, E Haddad, L Achouri… - … and Infectious Disease, 2019 - Elsevier
Loiasis is a vector-borne parasitic disease caused by the filarial Loa loa (L. loa). Definitive
diagnosis can be done by identifying and counting microfilariae in the peripheral blood by …

IgG4 serology of loiasis in three villages in an endemic area of south‐eastern Gabon

FS Touré, TG Egwang, P Millet, O Bain… - Tropical Medicine & …, 1998 - Wiley Online Library
Human filariasis due to Loa loa differs from other filariasis in that the majority of infected
subjects are without circulating microfilariae (occult loiasis). In search for alternative …

Loa loa infection detection using biomarkers: current perspectives

JP Akue, ER Eyang-Assengone… - Research and reports in …, 2018 - Taylor & Francis
Loa loa is originally a restricted filarial worm from central Africa and some west African
countries. However, numerous imported cases are being reported throughout the world due …

[HTML][HTML] Distinct loiasis infection states and associated clinical and hematological manifestations in patients from Gabon

L Veletzky, KA Eberhardt, J Hergeth… - Plos Neglected …, 2022 - journals.plos.org
Background Loiasis–a filarial disease endemic in Central and West Africa–is increasingly
recognized as significant individual and public health concern. While the understanding of …