The number of genome-level resources for non-model species continues to rapidly expand.
However, frog species remain underrepresented, with up to 90% of frog genera having no …

Much attention has been paid on amphibian peptides for their wide-ranging
pharmacological properties, clinical potential, and gene-encoded origin. More than 300 …

Antimicrobial peptides (AMPs) exhibit broad-spectrum antimicrobial activity, and have
promise as new therapeutic agents. While the adult North American bullfrog (Rana …

A large number of diverse antimicrobial peptides have been found in amphibian skins, and
many more remain to be identified. It is sufficiently easy to obtain amounts of gland …

We developed genetic resources for two N orth A merican frogs, L ithobates clamitans and P
seudacris regilla, widespread native amphibians that are potential indicator species of …

Amphibians' skin is a rich source of natural antimicrobial peptides (AMPs). These AMPs
exhibit marked inter-and intraspecific sequence divergence linked to the arms race between …

Reptiles are among the oldest known amniotes and are highly diverse in their morphology
and ecological niches. These animals have an evolutionarily ancient innate-immune system …

The skin secretion of the North American pickerel frog (Rana palustris) has long been known
to have pronounced noxious/toxic properties and to be highly effective in defence against …

Amphibian skin secretions are rich in antimicrobial peptides that act as important
components of an innate immune system. Here, we describe a novel “shotgun” skin peptide …

Peptide agents are regarded as hopeful candidates to solve life-threatening resistance of
pathogenic microorganisms to classic antibiotics due to their unique action mechanisms …