Transcriptional analysis of oxidative and nitrosative stress on oral opportunistic Candida albicans

RA Mohammed, KA Mohammad - Cellular and Molecular Biology, 2024 - cellmolbiol.org
The yeast Candida albicans is one of the most aggressive opportunistic pathogens in
immunocompromised patients. The ability of the yeast to withstand stresses and radicals is …

Systematic identification and characterization of five transcription factors mediating the oxidative stress response in Candida albicans

Y Cui, D Wang, CJ Nobile, D Dong, Q Ni, T Su… - Microbial …, 2024 - Elsevier
Candida albicans is an opportunistic human fungal pathogen that causes superficial and
systemic infections, particularly in immunocompromised individuals. In response to C …

Transcription factors regulating the response to oxidative stress in yeast

WS Moye-Rowley - Antioxidants and redox signaling, 2002 - liebertpub.com
A main avenue of defense against fungal infection uses oxidative killing of these and other
microorganisms. Consequently, the ability of fungi to withstand an oxidative challenge has …

Functional Characterization of a Novel Oxidative Stress Protection Protein in the Pathogenic Yeast Candida glabrata

J Usher, Y Chaudhari, V Attah, H Ho, K Haynes - Frontiers in Genetics, 2020 - frontiersin.org
Candida species are important pathogens of humans and the fourth most commonly isolated
pathogen from nosocomial blood stream infections. Although Candida albicans is the …

Fluconazole at subinhibitory concentrations induces the oxidative-and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida …

DM Arana, C Nombela, J Pla - Journal of antimicrobial …, 2010 - academic.oup.com
Objectives To analyse the oxidative and nitrosative stress response in Candida albicans
generated by fluconazole at subinhibitory concentrations, and the functional consequences …

Superoxide Dismutases in Candida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-induced SOD5 Gene

M Martchenko, AM Alarco, D Harcus… - Molecular biology of …, 2004 - Am Soc Cell Biol
Superoxide dismutases (SOD) convert superoxide radicals into less damaging hydrogen
peroxide. The opportunistic human pathogen Candida albicans is known to express …

Candida albicans Response Regulator Gene SSK1 Regulates a Subset of Genes Whose Functions Are Associated with Cell Wall Biosynthesis and Adaptation to …

N Chauhan, D Inglis, E Roman, J Pla, D Li… - Eukaryotic …, 2003 - Am Soc Microbiol
Ssk1p of Candida albicans is a putative response regulator protein of the Hog1 two-
component signal transduction system. In Saccharomyces cerevisiae, the phosphorylation …

Differential Response of Candida albicans and Candida glabrata to Oxidative and Nitrosative Stresses

M Cuéllar-Cruz, E López-Romero, E Ruiz-Baca… - Current …, 2014 - Springer
Invasive candidiasis is associated with high mortality in immunocompromised and
hospitalized patients. Candida albicans is the main pathological agent followed by Candida …

Cap1p is involved in multiple pathways of oxidative stress response in Candida albicans

Y Wang, YY Cao, XM Jia, YB Cao, PH Gao… - Free Radical Biology …, 2006 - Elsevier
Cap1p, a transcription factor in Candida albicans, is thought to participate in oxidative stress
tolerance, but the pathways involved are still unclear. The study was designed to reveal the …

CTA4 Transcription Factor Mediates Induction of Nitrosative Stress Response in Candida albicans

W Chiranand, I McLeod, H Zhou, JJ Lynn… - Eukaryotic …, 2008 - Am Soc Microbiol
This work has identified regulatory elements in the major fungal pathogen Candida albicans
that enable response to nitrosative stress. Nitric oxide (NO) is generated by macrophages of …