Advances in autism spectrum disorder (ASD) genetics have identified many genetic causes,
reflecting remarkable progress while at the same time identifying challenges such as …

More than a hundred genes have been identified that, when disrupted, impart large risk for
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …

There has been a surge of diagnosis of autism spectrum disorders (ASD) over the past
decade. While large, high powered genome screening studies of children with ASD have …

Highlights•High throughput genomic methods are rapidly increasing the pool of ASD
genes.•Heterogeneity, pleiotropy, and brain complexity complicate translation to …

Autism spectrum disorder (ASD) is a constellation of neurodevelopmental presentations with
high heritability and both phenotypic and genetic heterogeneity. To date, mutations in …

Genes that are mutated in Autism Spectrum Disorders (ASD) can be classified broadly as
either synaptic or developmental. But what if this is a false distinction? A recent spate of …

Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized
by social deficits and restrictive and/or repetitive behaviors. The breadth of ASD symptoms is …

Over the past several decades, progress in understanding the genetic basis of autism
spectrum disorder (ASD) has dramatically altered our conception of its genetic architecture …

Characterized by a combination of abnormalities in language, social cognition and mental
flexibility, autism is not a single disorder but a neurodevelopmental syndrome commonly …

Genetic studies have identified dozens of autism spectrum disorder (ASD) susceptibility
genes, raising two critical questions:(1) do these genetic loci converge on specific biological …