Encapsulation and release of calcein from herceptin-conjugated eLiposomes

MN Zafar, WG Pitt, GA Husseini - Heliyon, 2024 - cell.com
Achieving an optimal therapeutic level is crucial in effectively eradicating cancer cells during
treatment. However, conventional chemotherapy-associated systemic administration of …

Ultrasound-triggered herceptin liposomes for breast cancer therapy

A Elamir, S Ajith, NA Sawaftah, W Abuwatfa… - Scientific reports, 2021 - nature.com
The functionalization of liposomes with monoclonal antibodies is a potential strategy to
increase the specificity of liposomes and reduce the side-effects associated with …

The kinetics of calcein release from mixed targeted liposomes using ultrasound

NM AlSawaftah, GA Husseini… - Journal of Biomedical …, 2022 - ingentaconnect.com
Site-specific delivery of chemotherapeutics using actively targeted-stimuli-responsive
liposomes is a promising approach to enhance the therapeutic efficiency of anti-cancer …

Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer

AEE Ahmed - 2018 - dspace.aus.edu
Cancer is one of the deadliest diseases in this era. Since conventional treatment has many
side effects, its use is limited, which augments the need for new smart drug delivery systems …

Transferrin-modified liposomes triggered with ultrasound to treat HeLa cells

NM AlSawaftah, NS Awad, V Paul, PS Kawak… - Scientific reports, 2021 - nature.com
Targeted liposomes are designed to target specific receptors overexpressed on the surfaces
of cancer cells. This technique ensures site-specific drug delivery to reduce undesirable side …

Targeting breast cancer using hyaluronic acid-conjugated liposomes triggered with ultrasound

SM Ben Daya, V Paul, NS Awad… - Journal of …, 2021 - ingentaconnect.com
The successful targeting of tumors can be achieved by conjugating targeting moieties to
nanoparticles. These modifications allow nannocarriers to achieve greater targeting …

Effect of pegylation and targeting moieties on the ultrasound-mediated drug release from liposomes

NS Awad, V Paul, MS Mahmoud… - ACS Biomaterials …, 2019 - ACS Publications
The use of targeted liposomes encapsulating chemotherapy drugs enhances the specific
targeting of cancer cells, thus reducing the side effects of these drugs and providing patient …

Ultrasonically controlled albumin-conjugated liposomes for breast cancer therapy

NS Awad, V Paul, MH Al-Sayah… - Artificial Cells …, 2019 - Taylor & Francis
Targeted liposomes have high potentials in the specific and effective delivery of their loaded
therapeutic agents to the tumour site. Once at the tumour site, it is important that these …

Investigating the release mechanism of calcein from eLiposomes at higher temperatures

GA Husseini, WG Pitt, JB Williams… - Journal of Colloid …, 2014 - ingentaconnect.com
Numerous nanocarriers are currently being investigated as drug delivery vehicles for
transporting chemotherapeutics to cancer cells. Our research group has recently …

Effect of phospholipid head group on ultrasound-triggered drug release and cellular uptake of immunoliposomes

NS Awad, V Paul, NM AlSawaftah, GA Husseini - Scientific Reports, 2023 - nature.com
Liposomes are the most successful nanoparticles used to date to load and deliver
chemotherapeutic agents to cancer cells. They are nano-sized vesicles made up of …