Genetic testing in the evaluation of recipient candidates and living kidney donors

BK Lee, CP Thomas - Current opinion in nephrology and …, 2024 - journals.lww.com
The expansion of genomics into transplant medicine can provide improved diagnosis in
transplant candidates and potentially disease prediction in living donors. Transplant …

A pragmatic approach to selective genetic testing in kidney transplant candidates

P Nissaisorakarn, PK Fadakar, K Safa… - Frontiers in …, 2024 - frontiersin.org
Introduction Advances in the field of genetic testing have spurred its use in transplantation.
Potential benefits of genetic testing in transplant nephrology include diagnosis, treatment …

Evaluation of genetic kidney diseases in living donor kidney transplantation: towards precision genomic medicine in donor risk assessment

Y Caliskan, B Lee, AM Whelan, F Abualrub… - Current transplantation …, 2022 - Springer
Abstract Purpose of Review To provide a comprehensive update on the role of genetic
testing for the evaluation of kidney transplant recipient and living donor candidates. Recent …

[HTML][HTML] Genetic evaluation of living kidney donor candidates: a review and recommendations for best practices

CP Thomas, R Daloul, KL Lentine, R Gohh… - American Journal of …, 2023 - Elsevier
The growing accessibility and falling costs of genetic sequencing techniques has expanded
the utilization of genetic testing in clinical practice. For living kidney donation, genetic …

[HTML][HTML] The evolving role of diagnostic genomics in kidney transplantation

J Soraru, A Chakera, N Isbel… - Kidney International …, 2022 - Elsevier
Monogenic forms of heritable kidney disease account for a significant proportion of chronic
kidney disease (CKD) across both pediatric and adult patient populations and up to 11% of …

Clinical Genetic Testing in Kidney Disease and Transplantation: Logistical, Ethical, Legal, and Social Considerations

T Schiff - Current Transplantation Reports, 2023 - Springer
Abstract Purpose of Review The role of genetics in renal disorders is being increasingly
recognized, prompting the need to describe and address barriers to meaningful …

Clinical applications of genetic discoveries in kidney transplantation: a review

EP Marin, E Cohen, N Dahl - Kidney360, 2020 - journals.lww.com
Growth in knowledge of the genetics of kidney disease has revealed that significant
percentages of patients with diverse types of nephropathy have causative mutations …

Evaluation of Indications for Genetic Assessment in Living Kidney Transplant Donors and Relevant Canadian Practices in Light of the Current International Guidelines …

S Zahran, KF Bei, A Adil, PN Okoh… - Journal of the American …, 2023 - journals.lww.com
Background: End stage renal disease (ESRD) is a prevalent condition with tendency for
familial clustering. Living kidney donor transplantation is a superior treatment option …

[HTML][HTML] Is it time to utilize genetic testing for living kidney donor evaluation?

E Tantisattamo, UG Reddy, H Ichii, AJ Ferrey… - Nephron, 2022 - karger.com
Living donor kidney transplantation is an effective strategy to mitigate the challenges of solid
organ shortage. However, being a living kidney donor is not without risk, as donors may …

Evaluation of genetic renal diseases in potential living kidney donors

S Kuppachi, RJH Smith, CP Thomas - Current Transplantation Reports, 2015 - Springer
Better outcomes for living donor transplantation, together with the shortened waiting time
and the increasing gap between supply and demand for kidneys for transplantation, has led …