2'-Fucosyllactose restores the intestinal mucosal barrier in ulcerative colitis by inhibiting STAT3 palmitoylation and phosphorylation
J Li, Y Wei, C Liu, X Guo, Z Liu, L Zhang, S Bao, X Wu… - Clinical Nutrition, 2024 - Elsevier
Summary Background & aims 2'-Fucosyllactose (2'-FL), the primary constituent of human
milk oligosaccharides, has been identified as a potential regulator of inflammation in …
milk oligosaccharides, has been identified as a potential regulator of inflammation in …
2′-fucosyllactose ameliorates inflammatory bowel disease by modulating gut microbiota and promoting MUC2 expression
Q Yao, L Fan, N Zheng, C Blecker, V Delcenserie… - Frontiers in …, 2022 - frontiersin.org
Gut microbiota dysbiosis, together with goblet cells dysfunction has been observed in
ulcerative colitis cases. This study aims to evaluate the potential of 2′-fucosyllactose (2 …
ulcerative colitis cases. This study aims to evaluate the potential of 2′-fucosyllactose (2 …
The protective effect of 2'-Fucosyllactose on LPS-induced colitis suckling mice by ameliorating intestinal inflammation and modulating gut microbiota
H Lv, Q Li, Z Zhou, H Fang, Q Chen, Y Shuai - Food Bioscience, 2023 - Elsevier
Fucosyllactose (2′-FL), the main component of human milk oligosaccharides (HMOs), has
been shown to prevent intestinal diseases and its underlying mechanism remains unclear …
been shown to prevent intestinal diseases and its underlying mechanism remains unclear …
2′-Fucosyllactose and 3-Fucosyllactose Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal …
YJ Kim, HH Kim, CS Shin, JW Yoon, SM Jeon… - Nutrients, 2023 - mdpi.com
Ulcerative colitis is an inflammatory bowel disease (IBD) with relapsing and remitting
patterns, and it is caused by varied factors, such as the intestinal inflammation extent and …
patterns, and it is caused by varied factors, such as the intestinal inflammation extent and …
Combining 2'-fucosyllactose and galactooligosaccharides exerts anti-inflammatory effects and promotes gut health
S Park, Y Park, YJ Jeong, JG Oh, HJ Yoo… - Journal of Dairy … - journalofdairyscience.org
This study investigated the potential of 2'-Fucosyllactose (2'-FL) and
galactooligosaccharides (GOS) combinations as a novel and cost-effective substitute for …
galactooligosaccharides (GOS) combinations as a novel and cost-effective substitute for …
Effect of 2′-fucosyllactose supplementation on intestinal flora in mice with intestinal inflammatory diseases
A Li, W Ni, Y Li, X Zhang, J Yang, X Ma, X Jia… - International Dairy …, 2020 - Elsevier
The effects of human milk oligosaccharides (HMOs) and the main component, 2′-
fucosyllactose (2′-FL), on intestinal disorders were evaluated. A dextran sodium sulphate …
fucosyllactose (2′-FL), on intestinal disorders were evaluated. A dextran sodium sulphate …
Human milk oligosaccharide 2′-fucosyllactose alleviates DSS-induced ulcerative colitis via improving intestinal barrier function and regulating gut microbiota
X Chen, J Hu, J Yang, Q Yu, Y Chen, M Shen, L Rong… - Food Bioscience, 2024 - Elsevier
Ulcerative colitis (UC) is an inflammatory disease with the process recurrent and chronic.
Human milk oligosaccharide 2′ fucosyllactose (2′ FL) possessed unique immune …
Human milk oligosaccharide 2′ fucosyllactose (2′ FL) possessed unique immune …
[HTML][HTML] 2'-Fucosyllactose ameliorates chemotherapy-induced intestinal mucositis by protecting intestinal epithelial cells against apoptosis
G Zhao, J Williams, MK Washington, Y Yang… - Cellular and Molecular …, 2022 - Elsevier
Background & Aims Intestinal mucositis, a severe complication of antineoplastic
therapeutics, is characterized by mucosal injury and inflammation in the small intestine …
therapeutics, is characterized by mucosal injury and inflammation in the small intestine …
Flaxseed oligosaccharides alleviate DSS-induced colitis through modulation of gut microbiota and repair of the intestinal barrier in mice
Z Xu, W Chen, Q Deng, Q Huang, X Wang, C Yang… - Food & function, 2020 - pubs.rsc.org
Intestinal epithelial barrier dysfunction with dysbiosis of gut microbiota contributes to the
occurrence and acceleration of colitis. This study aimed to evaluate the effect of flaxseed …
occurrence and acceleration of colitis. This study aimed to evaluate the effect of flaxseed …
Galactooligosaccharide or 2′-fucosyllactose modulates gut microbiota and inhibits LPS/TLR4/NF-κB signaling pathway to prevent DSS-induced colitis aggravated by …
T Chen, C Wang, C Nie, X Yuan, A Tu… - Journal of Agricultural …, 2023 - ACS Publications
A high-fructose diet (HFrD) has been reported to exacerbate dextran sulfate sodium (DSS)-
induced colitis. 2′-Fucosyllactose (FL) and galactooligosaccharide (GOS) have been …
induced colitis. 2′-Fucosyllactose (FL) and galactooligosaccharide (GOS) have been …