In this study, amorphous solid dispersions (ASDs) of pterostilbene (PTR) with
polyvinylpyrrolidone polymers (PVP K30 and VA64) were prepared through milling, affirming …

The aim of our research was to improve the solubility and antioxidant activity of pterostilbene
(PTR) by developing a novel amorphous solid dispersion (ASD) with Soluplus®(SOL). DSC …

Rosmarinic acid (RA) is a natural antioxidant with neuroprotective properties; however, its
preventive and therapeutic use is limited due to its slight solubility and poor permeability …

The low bioaccessibility of hesperetin and piperine hampers their application as therapeutic
agents. Piperine has the ability to improve the bioavailability of many compounds when co …

Background: Naringenin (NAR) is a flavonoid with excellent antioxidant and neuroprotective
potential that is limited by its low solubility. Thus, solid dispersions with β-cyclodextrin (β …

Neurological disorders have been growing in recent years and are highly prevalent globally.
Resveratrol (RES) is a natural product from plant sources such as grape skins. This …

Pterostilbene (PTS) is a naturally occurring phytoalexin. PTS displays limited water
solubility, which consequently results in its diminished oral bioavailability. Therefore, a …

Pterostilbene, a stilbene compound, demonstrates neuroprotective effects through its
antioxidant and anti-inflammatory properties. However, pterostilbene exhibits low …

During cerebral ischemia/reperfusion (I/R) injury, oxidative stress and inflammation are
major contributors to disability. Finding compounds that reduce oxidative stress …

Inadequate aqueous solubilities of bioactive compounds hinder their ability to be developed
for medicinal applications. The potent antioxidant pterostilbene (PTB) is a case in point. The …