Genetic variation within intron 3 of the CACNA1C calcium channel gene is associated with
schizophrenia and bipolar disorder, but analysis of the causal variants and their effect is …

Calcium channel subunits, including CACNA1C, have been associated with multiple
psychiatric disorders. Specifically, genome wide association studies (GWAS) have …

Bipolar disorder (BD) and schizophrenia (SCZ) are highly heritable diseases that affect more
than 3% of individuals worldwide. Genome-wide association studies have strongly and …

Objectives Numerous genome-wide association studies have identified CACNA1C as one of
the top risk genes for schizophrenia. As a necessary post-genome-wide association study …

Thanks to the ongoing global efforts of genomics consortia, genome-wide association
studies are increasingly providing common variant genetic data that may be integrated with …

Objective There are theoretical reasons why comparing marker allele frequencies between
cases of different diseases, rather than with controls, may offer benefits. The samples may …

Objectives: Genome-wide association studies have identified a significant risk gene,
CACNA1C, for schizophrenia. In this study, we comprehensively investigated a large set of …

CACNA1I is implicated in the susceptibility to schizophrenia by large-scale genetic
association studies of single nucleotide polymorphisms. However, the channelopathy of …

CACNA1I (hCaV3. 3) encodes the α1 pore-forming subunit of human voltage-gated T-type
calcium channels. CaV3. 3 is expressed in a limited subset of neurons including GABAergic …

Genome-wide association studies suggest that genetic variation within L-type calcium
channel subunits confer risk to psychosis. The single nucleotide polymorphism at rs1006737 …