Ferroptosis has emerged as a promising therapeutic approach for glioma. However, its
efficacy is often compromised by the activated GPX4-reduced glutathione (GSH) system and …

As an emerging cancer treatment strategy, ferroptosis is distinguished by the perturbation of
lipid metabolism equilibrium and the accumulation of lipid peroxidation. However, the …

Glioma is the most common intracranial malignant tumor, and the current main standard
treatment option is a combination of tumor surgical resection, chemotherapy and …

As an emerging cancer treatment strategy, ferroptosis is greatly restricted by excessive
glutathione (GSH) in tumor microenvironment (TME) and low reactive oxygen species (ROS) …

As a promising new form of non-apoptotic regulated cell death, ferroptosis has potential as
an effective supplement to apoptosis-based cancer treatments. However, high intracellular …

Emerging evidence indicates that the activation of ferroptosis by glutathione peroxidase 4
(GPX4) inhibitors may be a prominent therapeutic strategy for tumor suppression. However …

The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …

Ferroptosis, a unique iron-dependent mode of cell death characterized by lipid peroxide
accumulation, holds significant potential for the treatment of glioblastoma (GBM). However …

Glioblastoma (GBM) is the most common malignant craniocerebral tumor. The treatment of
this cancer is difficult due to its high heterogeneity and immunosuppressive …

Ferroptosis holds great potential in cancer treatment, but its efficacy is severely limited by a
low Fenton reaction efficacy. Meanwhile, the interactive relationship between Ferroptosis …