The metagenome‐derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET)

H Zhang, RF Dierkes, P Perez‐Garcia… - The FEBS …, 2024 - Wiley Online Library
Polyethylene terephthalate (PET) is a widely used synthetic polymer and known to
contaminate marine and terrestrial ecosystems. Only few PET‐active microorganisms and …

New insights into the function and global distribution of polyethylene terephthalate (PET)-degrading bacteria and enzymes in marine and terrestrial metagenomes

D Danso, C Schmeisser, J Chow… - Applied and …, 2018 - Am Soc Microbiol
Polyethylene terephthalate (PET) is one of the most important synthetic polymers used
today. Unfortunately, the polymers accumulate in nature and to date no highly active …

The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity

H Zhang, P Perez-Garcia, RF Dierkes… - Frontiers in …, 2022 - frontiersin.org
Certain members of the Actinobacteria and Proteobacteria are known to degrade
polyethylene terephthalate (PET). Here, we describe the first functional PET-active enzymes …

Novel putative polyethylene terephthalate (PET) plastic degrading enzymes from the environmental metagenome

I Karunatillaka, L Jaroszewski… - … : Structure, Function, and …, 2022 - Wiley Online Library
Several plastic degrading enzymes have been described in the literature, most notably
PETases that are capable of hydrolyzing polyethylene terephthalate (PET) plastic. One of …

An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate

P Perez-Garcia, J Chow, E Costanzi… - Communications …, 2023 - nature.com
Polyethylene terephthalate (PET) is a commodity polymer known to globally contaminate
marine and terrestrial environments. Today, around 80 bacterial and fungal PET-active …

Exploring the global metagenome for plastic-degrading enzymes

P Pérez-García, D Danso, H Zhang, J Chow… - Methods in …, 2021 - Elsevier
Plastics are extensively used in our daily life, but they are also a major pollutant of our
biosphere accumulating in both the ocean and the land. In the recent years, few enzymes …

A new PETase from the human saliva metagenome and its functional modification via genetic code expansion in bacteria

MFM White, S Wallace - Angewandte Chemie International …, 2023 - Wiley Online Library
The discovery and engineering of new plastic degrading enzymes is an important challenge
in chemical biotechnology to enable transition to a more sustainable and circular plastics …

Positive charge introduction on the surface of thermostabilized PET hydrolase facilitates PET binding and degradation

A Nakamura, N Kobayashi, N Koga, R Iino - ACS Catalysis, 2021 - ACS Publications
A thermostable enzyme PET2, found in a metagenome library, has been engineered to
improve its hydrolytic activity against polyethylene terephthalate (PET). The PET2 wild-type …

Glacier as a source of novel polyethylene terephthalate hydrolases

X Qi, M Ji, CF Yin, NY Zhou, Y Liu - Environmental …, 2023 - Wiley Online Library
Polyethylene terephthalate (PET) is a major component of microplastic contamination
globally, which is now detected in pristine environments including Polar and mountain …

Discovery and genetic code expansion of a polyethylene terephthalate (PET) hydrolase from the human saliva metagenome for the degradation and bio …

B Eiamthong, P Meesawat, T Wongsatit… - Angewandte …, 2022 - Wiley Online Library
We report a bioinformatic workflow and subsequent discovery of a new polyethylene
terephthalate (PET) hydrolase, which we named MG8, from the human saliva metagenome …