Computer-made peptide RQ18 acts as a dual antifungal and antibiofilm peptide though membrane-associated mechanisms of action
CV Almeida, CFR de Oliveira… - Archives of Biochemistry …, 2024 - Elsevier
The spread of fungi resistant to conventional drugs has become a threatening problem. In
this context, antimicrobial peptides (AMPs) have been considered as one of the main …
this context, antimicrobial peptides (AMPs) have been considered as one of the main …
Development of a novel anti-biofilm peptide derived from profilin of Spodoptera frugiperda
ACB da Silva, JCO Sardi, DGL de Oliveira… - Biofouling, 2020 - Taylor & Francis
Candida yeast infections are the fourth leading cause of death worldwide. Peptides with
antimicrobial activity are a promising alternative treatment for such infections. Here, the …
antimicrobial activity are a promising alternative treatment for such infections. Here, the …
A potent candicidal peptide designed based on an encrypted peptide from a proteinase inhibitor
LH de Oliveira Almeida, SR Ramalho… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Antimicrobial peptides (AMP) represent an alternative in the treatment of fungal infections
associated with countless deaths. Here, we report a new AMP, named KWI-19, which was …
associated with countless deaths. Here, we report a new AMP, named KWI-19, which was …
[HTML][HTML] Antifungal and Antibiofilm Activities and the Mechanism of Action of Repeating Lysine-Tryptophan Peptides against Candida albicans
G Ramamourthy, J Park, C Seo, H J. Vogel, Y Park - Microorganisms, 2020 - mdpi.com
The rapid increase in the emergence of antifungal-resistant Candida albicans strains is
becoming a serious health concern. Because antimicrobial peptides (AMPs) may provide a …
becoming a serious health concern. Because antimicrobial peptides (AMPs) may provide a …
[HTML][HTML] Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants of C. auris
V Amann, AK Kissmann, V Mildenberger… - International Journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) represent a promising class of therapeutic biomolecules that
show antimicrobial activity against a broad range of microorganisms, including life …
show antimicrobial activity against a broad range of microorganisms, including life …
Differential interactions of the antimicrobial peptide, RQ18, with phospholipids and cholesterol modulate its selectivity for microorganism membranes
CV Almeida, CFR de Oliveira, EL Dos Santos… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Background Antimicrobial peptides (AMPs) are molecules with potential application
for the treatment of microorganism infections. We, herein, describe the structure, activity, and …
for the treatment of microorganism infections. We, herein, describe the structure, activity, and …
[HTML][HTML] Mechanisms of action of antimicrobial peptides ToAP2 and NDBP-5.7 against Candida albicans planktonic and biofilm cells
J do Nascimento Dias, C de Souza Silva… - Scientific reports, 2020 - nature.com
Candida albicans is a major cause of human infections, ranging from relatively simple to
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …
In vitro Antifungal Activity of a Novel Antimicrobial Peptide AMP-17 Against Planktonic Cells and Biofilms of Cryptococcus neoformans
L Yang, Z Tian, L Zhou, L Zhu, C Sun… - Infection and Drug …, 2022 - Taylor & Francis
Background Cryptococcus neoformans is a common human fungal pathogen in
immunocompromised people, as well as a prevalent cause of meningitis in HIV-infected …
immunocompromised people, as well as a prevalent cause of meningitis in HIV-infected …
[HTML][HTML] Antifungal Activity of Anionic Defense Peptides: Insight into the Action of Galleria mellonella Anionic Peptide 2
A Sowa-Jasiłek, A Zdybicka-Barabas… - International Journal of …, 2020 - mdpi.com
Anionic antimicrobial peptides constitute an integral component of animal innate immunity,
however the mechanisms of their antifungal activity are still poorly understood. The action of …
however the mechanisms of their antifungal activity are still poorly understood. The action of …
Antimicrobial peptides as a strategy to combat fungal biofilms
N Delattin, K De Brucker, K De Cremer… - Current Topics in …, 2017 - ingentaconnect.com
Invasive fungal infections caused by opportunistic fungal pathogens are associated with
high mortality rates, mainly due to the occurrence of genotypic and/or phenotypic resistance …
high mortality rates, mainly due to the occurrence of genotypic and/or phenotypic resistance …
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