Reactive oxygen species (ROS) accumulation inside the cells instigates oxidative stress,
activating stress-responsive genes. The viral strategies for promoting stressful conditions …

Lacking a self-contained metabolism network, viruses have evolved multiple mechanisms
for rewiring the metabolic system of their host to hijack the host's metabolic resources for …

Mammalian cells respond to various environmental stressors to form stress granules (SGs)
by arresting cyto‐plasmic mRNA, protein translation element, and RNA binding proteins …

Viruses require host cell metabolic reprogramming to satisfy their replication demands;
however, the mechanism by which the Newcastle disease virus (NDV) remodels nucleotide …

Abstract Background Newcastle Disease virus (NDV) causes severe and economically
significant disease in almost all birds. However, factors that affect NDV replication in host …

Newcastle disease virus (NDV) causes serious economic losses to the poultry industry. In
our previous study, we found that NDV induced a strong innate immune response in the …

Newcastle disease virus (NDV) causes severe infectious disease in poultry, and selectively
kills tumor cells by inducing apoptosis. In this report, we revealed the mechanisms …

Viral infections result in cellular stress responses, which can trigger protein translation
shutoff via phosphorylation of eukaryotic initiation factor 2 alpha (eIF2α). Newcastle disease …

Paramyxovirus establishes an intimate and complex interaction with the host cell to
counteract the antiviral responses elicited by the cell. Of the various pattern recognition …

Newcastle disease virus (NDV), a member of the Paramyxoviridae family, can activate
PKR/eIF2α signaling cascade to shutoff host and facilitate viral mRNA translation during …