[HTML][HTML] Novel therapeutic strategies for rare mutations in non-small cell lung cancer

Q Gou, Q Gou, X Gan, Y Xie - Scientific Reports, 2024 - nature.com
Lung cancer is still the leading cause of cancer-related mortality. Over the past two decades,
the management of non-small cell lung cancer (NSCLC) has undergone a significant …

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future directions

J Zhong, H Bai, Z Wang, J Duan, W Zhuang… - Frontiers of …, 2023 - Springer
With the improved understanding of driver mutations in non-small cell lung cancer (NSCLC),
expanding the targeted therapeutic options improved the survival and safety. However …

Recent progress in rare oncogenic drivers and targeted therapy for non-small cell lung cancer

Y Guo, R Cao, X Zhang, L Huang, L Sun… - OncoTargets and …, 2019 - Taylor & Francis
Non-small cell lung cancer (NSCLC) is frequently associated with oncogenic driver
mutations, which play an important role in carcinogenesis and cancer progression …

Targeting oncogenic drivers in lung cancer: Recent progress, current challenges and future opportunities

S Yoda, I Dagogo-Jack, AN Hata - Pharmacology & therapeutics, 2019 - Elsevier
Targeted therapies have changed the landscape of treatments for non-small cell lung cancer
(NSCLC). Specific targeted therapies have been approved for NSCLC patients harboring …

[HTML][HTML] Advancements in NSCLC: From Pathophysiological Insights to Targeted Treatments

J Xu, L Tian, W Qi, Q Lv, T Wang - American Journal of Clinical …, 2024 - journals.lww.com
With the global incidence of non-small cell lung cancer (NSCLC) on the rise, the
development of innovative treatment strategies is increasingly vital. This review underscores …

Targeting infrequent driver alterations in non-small cell lung cancer

MJ Nokin, C Ambrogio, E Nadal, D Santamaria - Trends in Cancer, 2021 - cell.com
The discovery of oncogenic driver mutations led to the development of targeted therapies
with non-small cell lung cancer (NSCLC) being a paradigm for precision medicine in this …

Novel therapeutic targets in non-small cell lung cancer

M Alamgeer, V Ganju, DN Watkins - Current opinion in pharmacology, 2013 - Elsevier
Oncogenic driver mutations frequently occur in lung cancer and play role in carcinogenesis.
These mutations are usually associated with distinct clinical and histological features and …

[HTML][HTML] Non-small-cell lung cancer: New rare targets—New targeted therapies—state of the art and future directions

K Stencel, I Chmielewska, J Milanowski, R Ramlau - Cancers, 2021 - mdpi.com
Simple Summary The use of novel therapeutic drugs in lung cancer has changed the
paradigm of the diagnosis and treatment of lung cancer. Due to the development of …

Targeting emerging molecular alterations in the treatment of non-small cell lung cancer: Current challenges and the way forward

U Malapelle, LA Muscarella, P Pisapia… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Driver molecular aberrations, such as EGFR and BRAF mutations, ALK and
ROS1 rearrangements, play an important role in the oncogenesis of non-small-cell lung …

The minority report: targeting the rare oncogenes in NSCLC

CE McCoach, RC Doebele - Current treatment options in oncology, 2014 - Springer
Opinion statement Lung cancer is still responsible for the highest number of cancer deaths
worldwide. Despite this fact, significant progress has been made in the treatment of non …