Designing scaffolds that can regulate the innate immune response and promote
vascularized bone regeneration holds promise for bone tissue engineering. Herein …

Exosomes have attracted increasing attention in tissue regeneration and repair due to their
roles in intercellular communication. Developing a customized delivery system is key to …

Large segmental bone regeneration remains a great challenge due to the lack of
vascularization in newly formed bone. Conventional strategies primarily combine bone …

Fulfilled angiogenesis and osteogenesis are prerequisites for achieving favorable
osseointegration of the bone implants. Incremental evidences have pinpointed that …

The reconstruction of severe alveolar bone defects remains a complex and challenging field
for clinicians. Three-dimensional-printed scaffolds can adapt precisely to the complicated …

Designing a multifunctional scaffold with osteogenic and angiogenic properties holds
promise for ideal bone regeneration. Innovative scaffold was here constructed by …

Designing scaffolds capable of inducing and guiding appropriate immune responses holds
promise for tissue repair/regeneration. Biofunctional scaffolds were here prepared by …

The treatment of bone defects is still an intractable clinical problem, despite the fact that
numerous treatments are currently available. In recent decades, bone engineering scaffolds …

Exosomes, nanoscale extracellular vesicles functioning as cell-to-cell communicators, are
an emerging promising therapeutic in the field of bone tissue engineering. Here, we report …

The repair of bone defects remains a huge clinical challenge. M2 macrophage-derived
exosomes (M2-Exos) can act as immunomodulators to promote fracture healing; however …