[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

Metal Complexes in cancer treatment: Journey so far

A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …

Coordination compounds in cancer: Past, present and perspectives

F Trudu, F Amato, P Vaňhara, T Pivetta… - Journal of applied …, 2015 - Elsevier
Metal-based coordination compounds have been used throughout the history of human
medicine to treat various diseases, including cancer. Since the discovery of cisplatin in …

Emerging Trends in Metal‐based Anticancer Agents: Drug Design to Clinical Trials and their Mechanism of Action

A Temesgen, HC Ananda Murthy, AZ Enyew… - …, 2023 - Wiley Online Library
Metal‐based therapeutic strategies have been effectively used to treat a number of diseases
since the ancient period. However, the issue that emerged at this time was the indistinct …

[HTML][HTML] Metallo-drugs in cancer therapy: Past, present and future

RL Lucaciu, AC Hangan, B Sevastre, LS Oprean - Molecules, 2022 - mdpi.com
Cancer treatments which include conventional chemotherapy have not proven very
successful in curing human malignancies. The failures of these treatment modalities include …

Metal complexes in cancer therapy–an update from drug design perspective

U Ndagi, N Mhlongo, ME Soliman - Drug design, development and …, 2017 - Taylor & Francis
In the past, metal-based compounds were widely used in the treatment of disease
conditions, but the lack of clear distinction between the therapeutic and toxic doses was a …

Novel metals and metal complexes as platforms for cancer therapy

M Frezza, S Hindo, D Chen… - Current …, 2010 - ingentaconnect.com
Metals are essential cellular components selected by nature to function in several
indispensable biochemical processes for living organisms. Metals are endowed with unique …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

Metal complexes in medicine an overview and update from drug design perspective

RK Sodhi, S Paul - Cancer Therapy & Oncology International …, 2019 - ideas.repec.org
Metals are essential cellular components selected by nature to function in several
indispensable biochemical processes for living organisms. Transition metal complexes are …

[HTML][HTML] Scope of organometallic compounds based on transition metal-arene systems as anticancer agents: starting from the classical paradigm to targeting multiple …

M Zaki, S Hairat, ES Aazam - RSC advances, 2019 - pubs.rsc.org
The advent of the clinically approved drug cisplatin started a new era in the design of
metallodrugs for cancer chemotherapy. However, to date, there has not been much success …