The major histocompatibility complex (MHC) multigene family encodes key pathogen‐
recognition molecules of the vertebrate adaptive immune system. Hyper‐polymorphism of …

Population bottlenecks can restrict variation at functional genes, reducing the ability of
populations to adapt to new and changing environments. Understanding how populations …

The major histocompatibility complex (MHC) plays a key role in pathogen recognition as a
part of the vertebrate adaptive immune system. The great diversity of MHC genes in natural …

Background Gene duplication has led to a most remarkable adaptation involved in
vertebrates' host-pathogen arms-race, the major histocompatibility complex (MHC) …

Recent advancements in sequencing technology have resulted in rapid progress in the
study of the major histocompatibility complex (MHC) in non-model avian species. Here, we …

The evolution of the major histocompatibility complex (MHC) is shaped by frequent gene
duplications and deletions, which generate extensive variation in the number of loci (gene …

The Major Histocompatibility Complex (MHC) is a hyper-polymorphic genomic region, which
forms a part of the vertebrate adaptive immune system and is crucial for intra-and extra …

Gene duplication and neofunctionalization are known to be important processes in the
evolution of phenotypic complexity. They account for important evolutionary novelties that …

Introduction The Major Histocompatibility Complex (MHC) of vertebrates is a dynamically
evolving multigene family primarily responsible for recognizing non-self peptide antigens …

The major histocompatibility complex (MHC) is a multigene family encoding a diversity of
molecules involved in the immune response and self–nonself recognition. Major …