ABSTRACT Mitogen-activated protein 3 kinase 1 (MAP3K1) has a plethora of cell type-
specific functions not yet fully understood. Herein, we describe a role for MAP3K1 in female …

Abstract Mitogen-Activated Protein 3 Kinase 1 (MAP3K1) is a dynamic signaling molecule
with a plethora of cell-type specific functions, most of which are yet to be understood. Here …

Wnt signaling effectors direct the development and adult remodeling of the female
reproductive tract (FRT); however, the role of non-canonical Wnt signaling has not been …

In-frame missense and splicing mutations (resulting in a 2 amino acid insertion or a 34
amino acid deletion) dispersed through the MAP3K1 gene tilt the balance from the male to …

Müllerian duct differentiation and development into the female reproductive tract is essential
for fertility, but mechanisms regulating these processes are poorly understood. WNT …

The murine female reproductive tract differentiates along the anteroposterior axis during
postnatal development. This process is marked by the emergence of distinct cell types in the …

The differentiation of endometrial stromal cells into decidual cells, termed decidualization, is
an integral step in the establishment of pregnancy. The mitogen-activated protein kinase …

Disruption of fetal growth results in severe consequences to human health, including
increased fetal and neonatal morbidity and mortality, as well as potential lifelong health …

Morphogenesis is a complex and highly coordinated process orchestrated by temporal
spatial activity of developmental pathways. How the different pathways interact to guide the …

A critical role of progesterone (P) during early pregnancy is to induce differentiation of the
endometrial stromal cells into specialized decidual cells that support the development of the …