Global crotonylome identifies EP300-regulated ANXA2 crotonylation in cumulus cells as a regulator of oocyte maturation
C Zhou, H Zeng, X Xiao, L Wang, L Jia, Y Shi… - International Journal of …, 2024 - Elsevier
Lysine crotonylation (Kcr), a newly discovered post-translational modification, played a
crucial role in physiology and disease progression. However, the roles of crotonylation in …
crucial role in physiology and disease progression. However, the roles of crotonylation in …
The mechanisms, regulations, and functions of histone lysine crotonylation
J Xie, J Ju, P Zhou, H Chen, S Wang, K Wang… - Cell Death …, 2024 - nature.com
Histone lysine crotonylation (Kcr) is a new acylation modification first discovered in 2011,
which has important biological significance for gene expression, cell development, and …
which has important biological significance for gene expression, cell development, and …
[HTML][HTML] Crotonylation and disease: Current progress and future perspectives
P Yang, Y Qin, L Zeng, Y He, Y Xie, X Cheng… - Biomedicine & …, 2023 - Elsevier
Histone lysine crotonylation was first identified as a new type of post-translational
modification in 2011. In recent years, prominent progress has been made in the study of …
modification in 2011. In recent years, prominent progress has been made in the study of …
Chromodomain protein CDYL acts as a crotonyl-CoA hydratase to regulate histone crotonylation and spermatogenesis
S Liu, H Yu, Y Liu, X Liu, Y Zhang, C Bu, S Yuan… - Molecular cell, 2017 - cell.com
Lysine crotonylation (Kcr) is a newly identified histone modification that is associated with
active transcription in mammalian cells. Here we report that the chromodomain Y-like …
active transcription in mammalian cells. Here we report that the chromodomain Y-like …
Proteomic profiling reveals the molecular control of oocyte maturation
H Sun, G Sun, H Zhang, H An, Y Guo, J Ge… - Molecular & Cellular …, 2023 - ASBMB
Meiotic maturation is an intricate and precisely regulated process orchestrated by various
pathways and numerous proteins. However, little is known about the proteome landscape …
pathways and numerous proteins. However, little is known about the proteome landscape …
Quantitative crotonylome analysis expands the roles of p300 in the regulation of lysine crotonylation pathway
H Huang, DL Wang, Y Zhao - Proteomics, 2018 - Wiley Online Library
Lysine crotonylation (Kcr) is a recently identified post‐translational modification (PTM) that is
regulated by an acetyltransferase, p300. The p300‐catalyzed histone Kcr is able to stimulate …
regulated by an acetyltransferase, p300. The p300‐catalyzed histone Kcr is able to stimulate …
The regulation and function of histone crotonylation
A Ntorla, JR Burgoyne - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Histone crotonylation is a newly identified epigenetic modification that has a pronounced
ability to regulate gene expression. It belongs to an expanding group of short chain lysine …
ability to regulate gene expression. It belongs to an expanding group of short chain lysine …
Protein crotonylation: An emerging regulator in DNA damage response
P Ji, G Zhang, Y Guo, H Song, X Yuan, X Hu, Z Guo… - Life Sciences, 2023 - Elsevier
DNA damage caused by internal or external factors lead to increased genomic instability
and various diseases. The DNA damage response (DDR) is a crucial mechanism that …
and various diseases. The DNA damage response (DDR) is a crucial mechanism that …
Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters
SK Dai, PP Liu, HZ Du, X Liu, YJ Xu, C Liu… - EMBO …, 2021 - embopress.org
Histone lysine crotonylation (Kcr), an evolutionarily conserved and widespread non‐acetyl
short‐chain lysine acylation, plays important roles in transcriptional regulation and disease …
short‐chain lysine acylation, plays important roles in transcriptional regulation and disease …
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism
T Xue, S Zhao, H Zhang, T Tang, L Zheng, J Jing, X Ge… - Iscience, 2023 - cell.com
Ovarian granulosa cells (GCs) in the follicle are the important mediator of steroidogenesis
and foster oocyte maturation. Evidences suggested that the function of GCs could be …
and foster oocyte maturation. Evidences suggested that the function of GCs could be …