This doctoral thesis embarks on a comprehensive journey of exploring the potential of
spectral X-ray imaging in medicine, employing advanced techniques and cutting-edge …

Objective. Differentiation of breast tissues is challenging in X-ray imaging because tissues
might share similar or even the same linear attenuation coefficients μ. Spectral computed …

The extra energy information provided by spectral x-ray imaging using novel photon
counting x-ray detectors may allow for improved decomposition of materials compared to …

Recent advances in the domain of energy-resolved semiconductor detectors stimulate
research in X-ray computed tomography (CT). However, the imperfections of these detectors …

Breast cancer is the most common cause of cancer death in Australian women. Current
pathological analysis examines a small section of tissue for cellular and plasma …

A single-energy CT provides a map of gray levels simply related to X-rays linear attenuation
coefficients, which could be very similar for different materials at a given energy. Images …

Compared to energy-integration, photon-counting detection of x-ray facilitates spectral
channelization (energy binning) in spectral CT and thus offers the opportunity of …

Following the development of energy-sensitive photon-counting detectors using high-Z
sensor materials, application of spectral x-ray imaging methods to clinical practice comes …

Objective: The conditioning (well-posedness) of basis materials (functions) and spectral
channelization play important roles in determining the performance of spectral imaging …

Purpose Compared to energy integration, photon‐counting x‐ray detection facilitates the
spectral channelization (energy binning) in spectral CT and thus offers the opportunity to …