Cytotoxic rhamnolipid micelles drive acute virulence in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic human pathogen that has developed multi-or
even pan-drug resistance toward most frontline and last resort antibiotics, leading to …
even pan-drug resistance toward most frontline and last resort antibiotics, leading to …
Inhibition of Macrophage Phagocytosis by Pseudomonas aeruginosa Rhamnolipids In Vitro and In Vivo
CD McClure, NL Schiller - Current microbiology, 1996 - Springer
Patients with cystic fibrosis often have chronic and ultimately lethal pulmonary infections with
Pseudomonas aeruginosa. In order to understand why these bacteria resist pulmonary …
Pseudomonas aeruginosa. In order to understand why these bacteria resist pulmonary …
Pseudomonas aeruginosa‐derived rhamnolipids subvert the host innate immune response through manipulation of the human beta‐defensin‐2 expression
J Dössel, U Meyer‐Hoffert, JM Schröder… - Cellular …, 2012 - Wiley Online Library
Pseudomonas aeruginosa is a well‐known cause of infections especially in compromised
patients. To neutralize this pathogen, the expression of antimicrobial factors in epithelial …
patients. To neutralize this pathogen, the expression of antimicrobial factors in epithelial …
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes
M Van Gennip, LD Christensen, M Alhede, R Phipps… - Apmis, 2009 - Wiley Online Library
Many of the virulence factors produced by the opportunistic human pathogen Pseudomonas
aeruginosa are quorum‐sensing (QS) regulated. Among these are rhamnolipids, which …
aeruginosa are quorum‐sensing (QS) regulated. Among these are rhamnolipids, which …
A new assay for rhamnolipid detection—important virulence factors of Pseudomonas aeruginosa
Rhamnolipids (RLs) are heterogeneous glycolipid molecules that are composed of one or
two l-rhamnose sugars and one or two β-hydroxy fatty acids, which can vary in their length …
two l-rhamnose sugars and one or two β-hydroxy fatty acids, which can vary in their length …
Rhamnolipids Are Virulence Factors That Promote Early Infiltration of Primary Human Airway Epithelia by Pseudomonas aeruginosa
L Zulianello, C Canard, T Köhler, D Caille… - Infection and …, 2006 - Am Soc Microbiol
The opportunistic bacterium Pseudomonas aeruginosa causes chronic respiratory infections
in cystic fibrosis and immunocompromised individuals. Bacterial adherence to the …
in cystic fibrosis and immunocompromised individuals. Bacterial adherence to the …
Pseudomonas aeruginosa biofilms: mechanisms of immune evasion
M Alhede, T Bjarnsholt, M Givskov, M Alhede - Advances in applied …, 2014 - Elsevier
The opportunistic gram-negative bacterium Pseudomonas aeruginosa is implicated in many
chronic infections and is readily isolated from chronic wounds, medical devices, and the …
chronic infections and is readily isolated from chronic wounds, medical devices, and the …
[引用][C] Shielding, a new pathogen defence mechanism against PMNs
P Cornelis - Microbiology, 2009 - microbiologyresearch.org
In an article published in this issue, Alhede et al.(2009) demonstrate that the opportunistic
pathogen Pseudomonas aeruginosa can react to the presence of PMNs by producing …
pathogen Pseudomonas aeruginosa can react to the presence of PMNs by producing …
[HTML][HTML] Pseudomonas aeruginosa rhamnolipid micelles deliver toxic metabolites and antibiotics into Staphylococcus aureus
BG Gdaniec, F Bonini, F Prodon, T Braschler, T Köhler… - IScience, 2022 - cell.com
Efficient delivery of toxic compounds to bacterial competitors is essential during interspecies
microbial warfare. Rhamnolipids (RLPs) are glycolipids produced by Pseudomonas and …
microbial warfare. Rhamnolipids (RLPs) are glycolipids produced by Pseudomonas and …
Rhamnolipids mediate an interspecies biofilm dispersal signaling pathway
Bacterial biofilms are problematic in natural and anthropogenic environments, and they
confer protective properties on their constituent cells, making them difficult to treat with …
confer protective properties on their constituent cells, making them difficult to treat with …