In clinical settings, tumor compression, trauma, surgical injury, and other types of injury can
cause hypothalamic damage, resulting in various types of hypothalamic dysfunction …

The hippocampus is vulnerable to uncontrollable stress and is enriched with oxytocin
receptors, but their interactive influences on hippocampal functioning are unknown. This …

The incidence of traumatic brain injury (TBI) has increased over the last years with an
important impact on public health. Many preclinical and clinical studies identified multiple …

Traumatic brain injury (TBI) is a major risk factor to develop epilepsy and cognitive
impairments. Neuropeptide oxytocin has been previously evidenced to produce antiepileptic …

The neuropeptide oxytocin (OT) modulates social behaviours and is an important anxiolytic
substance of the brain. However, sites of action and the intracellular signalling pathways …

Early life stress (ELS) is associated with altered stress responsivity, structural and functional
brain changes and an increased risk for the development of psychopathological conditions …

Oxytocin is a neuropeptide hormone that plays an important role in social bonding and
behavior. Recent studies indicate that oxytocin could be involved in the regulation of …

Ketamine is a popular recreational substance of abuse that induces persistent behavioral
deficits. Although disrupted oxytocinergic systems have been considered to modulate …

Background Hypothalamic obesity (HO) occurs in patients with tumors and lesions in the
medial hypothalamic region. In this study, a hyperphagic rat model of combined medial …

Long-term exposure to stressful stimuli can reduce hippocampal volume and cause
cognitive impairments, but the underlying mechanisms are not well understood …